Fine-tuning cellular physiology in response to intracellular and environmental cues requires
precise temporal and spatial control of gene expression. High-resolution imaging …

The spatial regulation of protein translation is an efficient way to create functional and
structural asymmetries in cells. Recent research has furthered our understanding of how …

We sought to create a comprehensive catalog of yeast genes whose transcript levels vary
periodically within the cell cycle. To this end, we used DNA microarrays and samples from …

ASH1 mRNA localizes to the bud tip in Saccharomyces cerevisiae to establish asymmetry of
HO expression, important for mating type switching. To visualize real time localization of the …

RNAs in cells are associated with RNA-binding proteins (RBPs) to form ribonucleoprotein
(RNP) complexes. The RBPs influence the structure and interactions of the RNAs and play …

Mating type in Saccharomyces cerevisiae is determined by two nonhomologous alleles,
MAT a and MAT α. These sequences encode regulators of the two different haploid mating …

Yeast cells can respond to growth on relatively poor nitrogen sources by increasing
expression of the enzymes for the synthesis of glutamate and glutamine and by increasing …

Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …

Cells use molecular motors, such as myosins, to move, position and segregate their
organelles. Class V myosins possess biochemical and structural properties that should …

Several bHLH proteins are involved in vertebrate neurogenesis, but those controlling early
stages of neuronal determination have not yet been identified. Here we describe a novel …