Clustered miRNAs and their role in biological functions and diseases
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
Non-coding RNAs, epigenetics, and cancer: tying it all together
HJ Ferreira, M Esteller - Cancer and Metastasis Reviews, 2018 - Springer
While only a small part of the human genome encodes for proteins, biological functions for
the so-called junk genome are increasingly being recognized through high-throughput …
the so-called junk genome are increasingly being recognized through high-throughput …
Evaluation of serum extracellular vesicle isolation methods for profiling miRNAs by next-generation sequencing
D Buschmann, B Kirchner, S Hermann… - Journal of …, 2018 - Taylor & Francis
Extracellular vesicles (EVs) are intercellular communicators with key functions in
physiological and pathological processes and have recently garnered interest because of …
physiological and pathological processes and have recently garnered interest because of …
microRNA exchange via extracellular vesicles in cancer
Cells utilize different means of inter‐cellular communication to function properly. Here, we
review the crosstalk between cancer cells and their surrounding environment through …
review the crosstalk between cancer cells and their surrounding environment through …
Transgenerational epigenetics: Integrating soma to germline communication with gametic inheritance
A Sharma - Mechanisms of Ageing and Development, 2017 - Elsevier
Evidence supporting germline mediated epigenetic inheritance of environmentally induced
traits has increasingly emerged over the past several years. Although the mechanisms …
traits has increasingly emerged over the past several years. Although the mechanisms …
Exosomes from nischarin-expressing cells reduce breast cancer cell motility and tumor growth
Exosomes are small extracellular microvesicles that are secreted by cells when intracellular
multivesicular bodies fuse with the plasma membrane. We have previously demonstrated …
multivesicular bodies fuse with the plasma membrane. We have previously demonstrated …
CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs
S Kaur, AG Elkahloun, A Arakelyan, L Young… - Scientific reports, 2018 - nature.com
Extracellular vesicles (EVs) mediate the intercellular transfer of RNAs, which alter gene
expression in target cells. EV heterogeneity has limited progress towards defining their …
expression in target cells. EV heterogeneity has limited progress towards defining their …
DLK1-DIO3 imprinted locus deregulation in development, respiratory disease, and cancer
JR Enterina, KSS Enfield, C Anderson… - Expert review of …, 2017 - Taylor & Francis
ABSTRACT Introduction: The imprinted DLK1-DIO3 locus at 14q32. 1–32.31 holds
biological significance in fetal development, whereby imprinting errors are causal to …
biological significance in fetal development, whereby imprinting errors are causal to …
Systematic assessment of small RNA profiling in human extracellular vesicles
Simple Summary Small RNA sequencing has been widely used for characterizing the
landscape of small non-coding RNAs—the most abundant cargo in extracellular vesicles …
landscape of small non-coding RNAs—the most abundant cargo in extracellular vesicles …
Protein binding partners of dysregulated miRNAs in Parkinson's disease serum
WP Ruf, A Freischmidt, V Grozdanov, V Roth… - Cells, 2021 - mdpi.com
Accumulating evidence suggests that microRNAs (miRNAs) are a contributing factor to
neurodegenerative diseases. Although altered miRNA profiles in serum or plasma have …
neurodegenerative diseases. Although altered miRNA profiles in serum or plasma have …