Pathogenesis and virulence of flavivirus infections
The Flavivirus genus consists of> 70 members including several that are considered
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …
significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be …
Revisiting dengue virus–host cell interaction: new insights into molecular and cellular virology
EG Acosta, A Kumar, R Bartenschlager - Advances in virus research, 2014 - Elsevier
Dengue virus (DENV) is an emerging mosquito-borne human pathogen that affects millions
of individuals each year by causing severe and potentially fatal syndromes. Despite intense …
of individuals each year by causing severe and potentially fatal syndromes. Despite intense …
Understanding the pathophysiology of COVID-19: could the contact system be the key?
S Meini, A Zanichelli, R Sbrojavacca, F Iuri… - Frontiers in …, 2020 - frontiersin.org
To date the pathophysiology of COVID-19 remains unclear: this represents a factor
determining the current lack of effective treatments. In this paper, we hypothesized a …
determining the current lack of effective treatments. In this paper, we hypothesized a …
Interaction of the human contact system with pathogens—an update
S Oehmcke-Hecht, J Köhler - Frontiers in immunology, 2018 - frontiersin.org
The name human contact system is related to its mode of action, as “contact” with artificial
negatively charged surfaces triggers its activation. Today, it is generally believed that the …
negatively charged surfaces triggers its activation. Today, it is generally believed that the …
Rapid discrimination of malaria-and dengue-infected patients sera using raman spectroscopy
Malaria and dengue have overlapping clinical symptoms and are prevalent in the same
geographic region (tropical and subtropical), hence precise diagnosis is challenging. The …
geographic region (tropical and subtropical), hence precise diagnosis is challenging. The …
Drug repositioning for dengue haemorrhagic fever by integrating multiple omics analyses
To detect drug candidates for dengue haemorrhagic fever (DHF), we employed a
computational drug repositioning method to perform an integrated multiple omics analysis …
computational drug repositioning method to perform an integrated multiple omics analysis …
Differential expression of serum/plasma proteins in various infectious diseases: specific or nonspecific signatures
Apart from direct detection of the infecting organisms or biomarker of the pathogen itself,
surrogate host markers are also useful for sensitive and early diagnosis of pathogenic …
surrogate host markers are also useful for sensitive and early diagnosis of pathogenic …
Identification of new spectral signatures associated with dengue virus infected sera
In a quest to use Raman spectroscopy as an optical diagnostic tool, we recorded Raman
spectra of 32 dengue virus (DENV)‐infected and 28 healthy sera samples in the near …
spectra of 32 dengue virus (DENV)‐infected and 28 healthy sera samples in the near …
Proteomic profiling of serum samples from chikungunya-infected patients provides insights into host response
Background Chikungunya is a highly debilitating febrile illness caused by Chikungunya
virus, a single-stranded RNA virus, which is transmitted by Aedes aegypti or Aedes …
virus, a single-stranded RNA virus, which is transmitted by Aedes aegypti or Aedes …
Clinical proteomics and cytokine profiling for dengue fever disease severity biomarkers
Dengue fever (DF) is a major global health burden with a pathophysiology that is still
incompletely understood. Biomarkers that predict and explain susceptibility to DF and its …
incompletely understood. Biomarkers that predict and explain susceptibility to DF and its …