Glycoursodeoxycholic acid regulates bile acids level and alters gut microbiota and glycolipid metabolism to attenuate diabetes

B Chen, Y Bai, F Tong, J Yan, R Zhang, Y Zhong… - Gut …, 2023 - Taylor & Francis
Accumulating evidence suggests that the bile acid regulates type 2 diabetes mellitus (T2DM)
through gut microbiota-host interactions. However, the mechanisms underlying such …

Advances in fecal microbiota transplantation for the treatment of diabetes mellitus

J Zhang, H Wang, Y Liu, M Shi, M Zhang… - Frontiers in Cellular …, 2024 - frontiersin.org
Diabetes mellitus (DM) refers to a group of chronic diseases with global prevalence,
characterized by persistent hyperglycemia resulting from various etiologies. DM can harm …

Gas chromatography–mass spectroscopy-based metabolomics analysis reveals potential biochemical markers for diagnosis of gestational diabetes mellitus

BA Raczkowska, P Mojsak, D Rojo, B Telejko… - Frontiers in …, 2021 - frontiersin.org
Due to many adverse effects of gestational diabetes mellitus (GDM) on the mother and fetus,
its diagnosis is crucial. The presence of GDM can be confirmed by an abnormal fasting …

Optimization of a GC-MS method for the profiling of microbiota-dependent metabolites in blood samples: An application to type 2 diabetes and prediabetes

P Mojsak, K Maliszewska, P Klimaszewska… - Frontiers in Molecular …, 2022 - frontiersin.org
Changes in serum or plasma metabolome may reflect gut microbiota dysbiosis, which is also
known to occur in patients with prediabetes and type 2 diabetes (T2DM). Thus, developing a …

Targeted and untargeted metabolomic approach for GDM diagnosis

I Burzynska-Pedziwiatr, D Dudzik… - Frontiers in Molecular …, 2023 - frontiersin.org
Gestational diabetes mellitus (GDM) is a disorder which manifests itself for the first time
during pregnancy and is mainly connected with glucose metabolism. It is also known that …

Metabolomic heterogeneity of ageing with ethnic diversity: a step closer to healthy ageing

D Trivedi, KA Hollywood, Y Xu, FCW Wu, DK Trivedi… - Metabolomics, 2025 - Springer
Objective A metabolomics approach was adopted to profile serum metabolomes in middle-
aged and elderly men of different ethnicities from the Northwest of England, UK. Methods …

Serum and urine metabolomics study revealed the amelioration of Gynura bicolor extract on high fat diet-fed and streptozotocin-induced type 2 diabetic mice based on …

X Ding, Y Tian, L Huang, Y Gai, H Lyu, M Li… - … of Pharmaceutical and …, 2023 - Elsevier
Type 2 diabetes mellitus (T2DM) has been the most prevalent disease and has become a
serious public health threat worldwide. Gynura bicolor (Willd.) DC.(GB) contains a variety of …