The η-class carbonic anhydrases as drug targets for antimalarial agents

CT Supuran, C Capasso - Expert opinion on therapeutic targets, 2015 - Taylor & Francis
Introduction: The η-class of carbonic anhydrases (CAs, EC 4.2. 1.1) was recently discovered
as the sixth genetic family of this metalloenzyme superfamily, and seems to be present only …

Malaria distribution and performance of malaria diagnostic methods in Malaysia (1980–2019): a systematic review

MAFA Rahim, MB Munajat, ZM Idris - Malaria journal, 2020 - Springer
Background Malaysia has already achieved remarkable accomplishments in reaching zero
indigenous human malaria cases in 2018. Prompt malaria diagnosis, surveillance and …

Malaria elimination in Malaysia and the rising threat of Plasmodium knowlesi

AZ Chin, MCM Maluda, J Jelip, MSB Jeffree… - Journal of physiological …, 2020 - Springer
Background Malaria is a major public-health problem, with over 40% of the world's
population (more than 3.3 billion people) at risk from the disease. Malaysia has committed to …

The zinc coordination pattern in the η-carbonic anhydrase from Plasmodium falciparum is different from all other carbonic anhydrase genetic families

G De Simone, A Di Fiore, C Capasso… - Bioorganic & medicinal …, 2015 - Elsevier
In this Letter we reinvestigate the sequence analysis and report a homology model of the
carbonic anhydrase (CA, EC 4.2. 1.1) from the protozoan parasite Plasmodium falciparum …

Antimalarial properties and molecular docking analysis of compounds from Dioscorea bulbifera L. as new antimalarial agent candidates

P Chaniad, M Mungthin, A Payaka… - … medicine and therapies, 2021 - Springer
Background At present, the emergence and spread of antimalarial drug resistance has
become a significant problem worldwide. There has been a challenge in searching for …

[HTML][HTML] Nested multiplex PCR for identification and detection of human Plasmodium species including Plasmodium knowlesi

M Miguel-Oteo, AI Jiram, TH Ta-Tang, M Lanza… - Asian Pacific journal of …, 2017 - Elsevier
Objective To develop a new technique for diagnosis of Plasmodium knowlesi and at the
same time to be able to discriminate among the diverse species of Plasmodium causing …

Sulfonamide inhibition studies of the η-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum

D Vullo, S Del Prete, GM Fisher, KT Andrews… - Bioorganic & Medicinal …, 2015 - Elsevier
The η-carbonic anhydrases (CAs, EC 4.2. 1.1) were recently discovered as the sixth genetic
class of this metalloenzyme superfamily, and are so far known only in protozoa, including …

Malaria diagnostics: now and the future

PL Chiodini - Parasitology, 2014 - cambridge.org
Light microscopy of stained blood films is still the mainstay of malaria diagnosis in many
regions, but its pre-eminence is threatened by accurate and sensitive rapid diagnostic tests …

Defining the ecological and evolutionary drivers of Plasmodium knowlesi transmission within a multi-scale framework

G Davidson, TH Chua, A Cook, P Speldewinde… - Malaria journal, 2019 - Springer
Plasmodium knowlesi is a zoonotic malaria parasite normally residing in long-tailed and pig-
tailed macaques (Macaca fascicularis and Macaca nemestrina, respectively) found …

Helminth Parasites Alter Protection against Plasmodium Infection

VH Salazar-Castañon… - BioMed research …, 2014 - Wiley Online Library
More than one‐third of the world's population is infected with one or more helminthic
parasites. Helminth infections are prevalent throughout tropical and subtropical regions …