Physical activity improves overall health and reduces the risk of many negative health
outcomes and may be effective in improving cognition, independent functioning, and …

Aging, hypertension, diabetes, hypoxia/obstructive sleep apnea (OSA), obesity, vitamin
B12/folate deficiency, depression, and traumatic brain injury synergistically promote diverse …

There is currently no established therapy to treat or prevent Alzheimer's disease. The
ketogenic diet supplies an alternative cerebral metabolic fuel, with potential neuroprotective …

Importance Converging evidence suggests that Alzheimer disease (AD) involves insulin
signaling impairment. Patients with AD and individuals at risk for AD show reduced glucose …

Abstract The Wisconsin Registry for Alzheimer's Prevention is a longitudinal observational
cohort study enriched with persons with a parental history (PH) of probable Alzheimer's …

Vascular dementia (VaD) is the second leading form of dementia after Alzheimer's disease
(AD) plaguing the elderly population. VaD is a progressive disease caused by reduced …

Background Physical activity may attenuate age-related cognitive decline by improving
cerebrovascular function. The aim of this study was therefore to investigate effects of aerobic …

Over two-thirds of individuals aged 65 and older are obese or overweight in the United
States. Epidemiological data show an association between the degree of adiposity and …

Arterial spin labeling (ASL) magnetic resonance imaging uses arterial blood water as an
endogenous tracer to measure cerebral blood flow (CBF). In this review, based on ASL …

Improving cerebrovascular function may be a key mechanism whereby a healthy lifestyle, of
which a healthy diet combined with increased physical activity levels is a cornerstone …