The field of hematopoietic stem cell transplant (HSCT) has made ground-breaking progress
in the treatment of many malignant and nonmalignant conditions. It has also pioneered the …

Antigen‐presenting molecules vary between individuals of the same species, making it more
difficult for pathogens to evade immune recognition and spread through the whole …

Previously, two men were cured of HIV-1 through CCR5Δ32 homozygous (CCR5Δ32/Δ32)
allogeneic adult stem cell transplant. We report the first remission and possible HIV-1 cure in …

Although children have been largely spared from coronavirus disease 2019 (COVID-19), the
emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of …

The adaptive immune system uses several strategies to generate a repertoire of T-and B-cell
antigen receptors with sufficient diversity to recognize the universe of potential pathogens. In …

Background Umbilical-cord blood as an alternative to bone marrow for hematopoietic stem-
cell transplantation may lower the risk of graft-versus-host disease (GVHD). Methods We …

Infection is the leading cause of non-relapse mortality after allogeneic haematopoietic cell
transplantation (HCT). This occurs as a result of dysfunction to the host immune system from …

Hematopoietic cell transplantation (HCT) can be curative for selected malignant and
nonmalignant diseases. 1-13 However, utilization and success of HCT are limited by several …

Innate natural killer (NK) cells are diverse at the single-cell level because of variegated
expressions of activating and inhibitory receptors, yet the developmental roots and …

OBJECTIVE: The number of umbilical cord blood transplants is increasing worldwide. At this
time, it is important to evaluate their results and to compare the outcome of umbilical cord …