HIV and tuberculosis–science and implementation to turn the tide and reduce deaths

AD Harries, SD Lawn, H Getahun… - African Journal of …, 2012 - journals.lww.com
Introduction: Every year, HIV-associated tuberculosis (TB) deprives 350,000 mainly young
people of productive and healthy lives. People die because TB is not diagnosed and treated …

[HTML][HTML] Comparison of two active case-finding strategies for community-based diagnosis of symptomatic smear-positive tuberculosis and control of infectious …

EL Corbett, T Bandason, T Duong, E Dauya… - The Lancet, 2010 - thelancet.com
Background Control of tuberculosis in settings with high HIV prevalence is a pressing public
health priority. We tested two active case-finding strategies to target long periods of …

Tuberculosis screening in high human immunodeficiency virus prevalence settings: turning promise into reality [State of the art series. Active case finding/screening …

EL Corbett, P MacPherson - The international journal of …, 2013 - ingentaconnect.com
Twenty years of sky-high tuberculosis (TB) incidence rates and high TB mortality in high
human immunodeficiency virus (HIV) prevalence countries have so far not been matched by …

Tuberculosis prevalence after 4 years of population-wide systematic TB symptom screening and universal testing and treatment for HIV in the HPTN 071 (PopART) …

E Klinkenberg, S Floyd, K Shanaube, L Mureithi… - PLoS …, 2023 - journals.plos.org
Background Tuberculosis (TB) prevalence remains persistently high in many settings, with
new or expanded interventions required to achieve substantial reductions. The HIV …

Durations of asymptomatic, symptomatic, and care-seeking phases of tuberculosis disease with a Bayesian analysis of prevalence survey and notification data

CC Ku, P MacPherson, ME Khundi, RH Nzawa Soko… - BMC medicine, 2021 - Springer
Background Ratios of bacteriologically positive tuberculosis (TB) prevalence to notification
rates are used to characterise typical durations of TB disease. However, this ignores the …

Characteristics of patients with smear-negative pulmonary tuberculosis (TB) in a region with high TB and HIV prevalence

LC Campos, MVV Rocha, DMC Willers, DR Silva - PloS one, 2016 - journals.plos.org
Introduction Smear-negative pulmonary TB (SNPT) represents 30–60% of all pulmonary TB
cases. The mortality of these patients can reach 25% in populations with high prevalence of …

Choosing algorithms for TB screening: a modelling study to compare yield, predictive value and diagnostic burden

AH van't Hoog, I Onozaki, K Lonnroth - BMC infectious diseases, 2014 - Springer
Background To inform the choice of an appropriate screening and diagnostic algorithm for
tuberculosis (TB) screening initiatives in different epidemiological settings, we compare …

The cost-effectiveness of routine tuberculosis screening with Xpert MTB/RIF prior to initiation of antiretroviral therapy: a model-based analysis

JR Andrews, SD Lawn, C Rusu, R Wood, F Noubary… - Aids, 2012 - journals.lww.com
Background: In settings with high tuberculosis (TB) prevalence, 15–30% of HIV-infected
individuals initiating antiretroviral therapy (ART) have undiagnosed TB. Such patients are …

Epidemiology of pediatric tuberculosis in Kenya and risk factors for mortality during treatment: a national retrospective cohort study

DO Onyango, CM Yuen, E Masini, MW Borgdorff - The Journal of pediatrics, 2018 - Elsevier
Objectives To describe the epidemiology of childhood tuberculosis (TB) in Kenya, assess
the magnitude of TB/human immunodeficiency virus (HIV) co-infection and identify risk …

Risk factors for mortality in smear-negative tuberculosis suspects: a cohort study in Harare, Zimbabwe

P MacPherson, M Dimairo, T Bandason… - … of tuberculosis and …, 2011 - ingentaconnect.com
OBJECTIVE: To investigate mortality rates and risk factors for death among smear-negative
tuberculosis (TB) suspects. DESIGN: Cohort study nested within a cluster-randomised trial of …