miR-1246 is a microRNA firstly recognized through application of a high throughput
sequencing technique in human embryonic stem cells. Subsequent studies have shown the …

Micro-RNAs (miRNAs) control gene expression at the post-transcriptional level and are
widely involved in carcinogenesis, playing a role as both oncogenes and tumor …

Exosomes are extracellular vesicles of endosomal origin, ranging from 30 to 150 nm in
diameter, that mediate intercellular transfer of various biomolecules, such as proteins, lipids …

Epithelial ovarian cancer (EOC) is one of the leading cancers in women, with high-grade
serous ovarian cancer (HGSOC) being the most common and lethal subtype of this disease …

Extracellular vesicles (EVs), including exosomes, are key factors of intercellular
communication, performing both local and distant transfers of bioactive molecules. The …

Background Despite numerous reports on the alterations of microRNA-1246 (miR-1246)
expression level in digestive system cancers, its role in gastrointestinal cancers (GICs) …

The rising incidence and mortality of early-onset colorectal cancer (EOCRC) emphasize the
urgent need for effective non-invasive screening. Circulating microRNAs (miRNAs) have …

Background. MicroRNA‐1246 (miR‐1246), an oncomiR that regulates the expression of
multiple cancer‐related genes, has been attracted and studied as a promising indicator of …

Colorectal cancer (CRC) remains the second most common cause of cancer-related
mortality worldwide, necessitating advancements in early detection and innovative treatment …

目的探讨外泌体miR-1246 对帕金森病(PD) 的诊断价值. 方法收集2022 年9 月至2023 年4
月在新疆医科大学第二附属医院住院的30 例PD 患者(PD 组) 和接受体检的30 …