The immune and skeletal systems share a variety of molecules, including cytokines,
chemokines, hormones, receptors, and transcription factors. Bone cells interact with immune …

Psoriasis is an immune-mediated disease associated with skin and joint inflammation that
affects large proportions of populations worldwide. It is a heritable disease: individuals' …

The synovial tissue is an immunologically challenging environment where, under
homeostatic conditions, highly specialized subsets of immune-regulatory macrophages and …

The role of the synovial fibroblast in rheumatoid arthritis... : Current Opinion in
Rheumatology The role of the synovial fibroblast in rheumatoid arthritis pathogenesis …

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by destructive
hyperplasia of the synovium. Fibroblast‐like synoviocytes (FLS) are a major component of …

Acute kidney injury (AKI) is a potentially fatal syndrome characterized by a rapid decline in
kidney function caused by ischemic or toxic injury to renal tubular cells. The widely used …

Objective To investigate the molecular mechanism underlying inflammation‐related ectopic
new bone formation in ankylosing spondylitis (AS). Methods Spinal tissues and sera were …

Background and Purpose Neutrophilic inflammation is a critical pathogenic factor in
psoriasis. The therapeutic applicability of palbociclib, a cyclin‐dependent kinase 4 and 6 …

Background Neutrophilic inflammation, characterized by dysregulated neutrophil activation,
triggers a variety of inflammatory responses such as chemotactic infiltration, oxidative bursts …

Background Fibroblast-like synoviocytes (FLSs), which can migrate and directly invade the
cartilage and the bone, are crucial players in joint damage in rheumatoid arthritis (RA) …