The INhibitor of Growth (ING) family of plant homeodomain (PHD) proteins induce apoptosis
and regulate gene expression through stress-inducible binding of phospholipids with …

Background Basal cell carcinoma (BCC) of the skin is the most common human cancer. The
genetic alterations underlying BCC development are only partly understood. Objectives To …

In hibitor of G rowth 1 (ING1) was identified and characterized as a “candidate” tumor
suppressor gene in 1996. Subsequently, four more genes, also characterized as “candidate” …

Characterization of the transcriptional regulatory network of the normal cell cycle is essential
for understanding the perturbations that lead to cancer. However, the complete set of cycling …

The aim of this study was to identify key genes associated with gliomas and glioblastoma
and to explore the related signaling pathways. Gene expression profiles of three glioma …

Objective Polycystic ovary syndrome (PCOS) is a common endocrine disorder with high
incidence. Recently it has been implicated as a significant risk factor for endometrial cancer …

Histone deacetylase (HDAC) inhibitors are in clinical development for several diseases,
including cancers and neurodegenerative disorders. HDACs 1 and 2 are among the targets …

Purpose: This study determines which clinical features predict positive test results among
samples submitted for DNA-based diagnostic nevoid basal cell carcinoma syndrome …

Abstract ING genes (ING1–5) were identified has tumor suppressor genes. ING proteins are
characterized as Type II TSGs since they are involved in the control of cell proliferation …

Phospholipid signaling has clear connections to a wide array of cellular processes,
particularly in gene expression and in controlling the chromatin biology of cells. However …