Tandem Prins cyclization is a versatile method for the synthesis of fused/bridged/
spirotetrahydropyran scaffolds. Therefore, it has become a powerful tool for the …

In the quest for synthesizing biologically important natural products, medicinal chemists
embark on an endless journey. This review focuses on the reports published towards the …

Serendipitous formation of cyclic β-ketosulfones is observed when sulfone-tethered
arylalkynols are reacted with base. The reaction involves a base-promoted propargyl …

A metal-free Lewis acid-initiated protocol for the synthesis of highly substituted 3-
(dihydrofuran-3 (2 H)-ylidene) isobenzofuran-1 (3 H)-imines from 2-(4-hydroxybut-1-yn-1-yl) …

A method for remote radical C–H alkynylation and amination of diverse aliphatic alcohols
has been developed. The reaction features a copper nucleophile complex formed in situ as …

A mechanochemical and solvent/catalyst‐free functionalization of olefins with hypervalent
iodine reagents has been developed, enabling the synthesis of 1, 3‐dioxygenated …

Lewis-acid-catalyzed 5-endo-dig reductive hydroalkoxylation cascade on propargylic N-
hydroxylamine gave expedient, stereoselective access to isoxazolidine derivatives. The …

Reported herein is a novel reaction engineering protocol to enhance the efficiency of a
transition metal-catalysed process by strategically preventing ligand degradation. Based on …

Asymmetric sequential hydrogenations of α‐methylene γ‐or δ‐keto carboxylic acids are
established in one‐pot using a bimetallic Ru/Ru catalyst system, achieving the …

TMSOTf‐mediated 5‐endo‐dig aminocyclization followed by N‐to C‐[1, 3]‐sulfonyl
migration on N¬‐homopropargyl hydroxylamines gave diastereoselective access to …