Anaplastic thyroid carcinoma: an update

A Jannin, A Escande, A Al Ghuzlan, P Blanchard… - Cancers, 2022 - mdpi.com
Simple Summary Anaplastic thyroid carcinoma (ATC) has a dismal prognostic.
Chemotherapy and radiotherapy are the mainstem options for patients with ATC. In selected …

American Head and Neck Society Endocrine Surgery Section and International Thyroid Oncology Group consensus statement on mutational testing in thyroid cancer …

DC Shonka Jr, A Ho, AV Chintakuntlawar… - Head & …, 2022 - Wiley Online Library
Background The development of systemic treatment options leveraging the molecular
landscape of advanced thyroid cancer is a burgeoning field. This is a multidisciplinary …

Thyroid carcinoma, version 2.2022, NCCN clinical practice guidelines in oncology

RI Haddad, L Bischoff, D Ball, V Bernet… - Journal of the National …, 2022 - jnccn.org
Differentiated thyroid carcinomas is associated with an excellent prognosis. The treatment of
choice for differentiated thyroid carcinoma is surgery, followed by radioactive iodine ablation …

2021 American thyroid association guidelines for management of patients with anaplastic thyroid cancer: American thyroid association anaplastic thyroid cancer …

KC Bible, E Kebebew, J Brierley, JP Brito… - Thyroid, 2021 - liebertpub.com
Background: Anaplastic thyroid cancer (ATC) is a rare but highly lethal form of thyroid
cancer. Since the guidelines for the management of ATC by the American Thyroid …

[HTML][HTML] Dabrafenib plus trametinib in patients with BRAF V600E-mutant anaplastic thyroid cancer: updated analysis from the phase II ROAR basket study

V Subbiah, RJ Kreitman, ZA Wainberg, JY Cho… - Annals of …, 2022 - Elsevier
Background Combined therapy with dabrafenib plus trametinib was approved in several
countries for treatment of BRAF V600E-mutant anaplastic thyroid cancer (ATC) based on an …

Evaluation of overall survival in patients with anaplastic thyroid carcinoma, 2000-2019

A Maniakas, R Dadu, NL Busaidy, JR Wang… - JAMA …, 2020 - jamanetwork.com
Importance Anaplastic thyroid carcinoma (ATC) historically has a 4-month median overall
survival (OS) from time of diagnosis, with disease-specific mortality approaching 100%. The …

Combination of lenvatinib and pembrolizumab is an effective treatment option for anaplastic and poorly differentiated thyroid carcinoma

C Dierks, J Seufert, K Aumann, J Ruf, C Klein, S Kiefer… - Thyroid, 2021 - liebertpub.com
Background: Anaplastic thyroid carcinoma (ATC) and metastatic poorly differentiated thyroid
carcinomas (PDTCs) are rare aggressive malignancies with poor overall survival (OS) …

Surgery After BRAF-Directed Therapy Is Associated with Improved Survival in BRAFV600E Mutant Anaplastic Thyroid Cancer: A Single-Center Retrospective Cohort …

X Zhao, JR Wang, R Dadu, NL Busaidy, L Xu… - Thyroid, 2023 - liebertpub.com
Background: The aim of this study was to describe the oncologic outcomes of patients with
BRAFV600E-mutated anaplastic thyroid cancer (ATC) who had neoadjuvant BRAF-directed …

Molecular targets of tyrosine kinase inhibitors in thyroid cancer

P Fallahi, SM Ferrari, MR Galdiero, G Varricchi… - Seminars in cancer …, 2022 - Elsevier
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising
incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with …

Advances in the management of anaplastic thyroid carcinoma: transforming a life-threatening condition into a potentially treatable disease

I Califano, A Smulever, F Jerkovich, F Pitoia - Reviews in Endocrine and …, 2024 - Springer
Anaplastic thyroid cancer (ATC) is an infrequent thyroid tumor that usually occurs in elderly
patients. There is often a history of previous differentiated thyroid cancer suggesting a …