The integration of negative affect, pain and cognitive control in the cingulate cortex
It has been argued that emotion, pain and cognitive control are functionally segregated in
distinct subdivisions of the cingulate cortex. However, recent observations encourage a …
distinct subdivisions of the cingulate cortex. However, recent observations encourage a …
Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways
Obsessive-compulsive disorder (OCD) affects approximately 2–3% of the population and is
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …
characterized by recurrent intrusive thoughts (obsessions) and repetitive behaviors or …
Meta-analytic evidence for a superordinate cognitive control network subserving diverse executive functions
Classic cognitive theory conceptualizes executive functions as involving multiple specific
domains, including initiation, inhibition, working memory, flexibility, planning, and vigilance …
domains, including initiation, inhibition, working memory, flexibility, planning, and vigilance …
Obsessive-compulsive disorder is associated with broad impairments in executive function: A meta-analysis
Obsessive-compulsive disorder (OCD) is a serious and often chronically disabling condition.
The current dominant model of OCD focuses on abnormalities in prefrontal-striatal circuits …
The current dominant model of OCD focuses on abnormalities in prefrontal-striatal circuits …
Voxel-wise meta-analysis of grey matter changes in obsessive–compulsive disorder
J Radua, D Mataix-Cols - The British Journal of Psychiatry, 2009 - cambridge.org
BackgroundSpecific cortico-striato-thalamic circuits are hypothesised to mediate the
symptoms of obsessive–compulsive disorder (OCD), but structural neuroimaging studies …
symptoms of obsessive–compulsive disorder (OCD), but structural neuroimaging studies …
Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder: the orbitofronto-striatal model revisited
Obsessive-compulsive disorder (OCD) is a common, heritable and disabling
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
neuropsychiatric disorder. Theoretical models suggest that OCD is underpinned by …
Probing compulsive and impulsive behaviors, from animal models to endophenotypes: a narrative review
NA Fineberg, MN Potenza, SR Chamberlain… - …, 2010 - nature.com
Failures in cortical control of fronto-striatal neural circuits may underpin impulsive and
compulsive acts. In this narrative review, we explore these behaviors from the perspective of …
compulsive acts. In this narrative review, we explore these behaviors from the perspective of …
Altered corticostriatal functional connectivity in obsessive-compulsive disorder
Context Neurobiological models of obsessive-compulsive disorder (OCD) emphasize
disturbances in the function and connectivity of brain corticostriatal networks, or “loops.” …
disturbances in the function and connectivity of brain corticostriatal networks, or “loops.” …
Error processing and inhibitory control in obsessive-compulsive disorder: a meta-analysis using statistical parametric maps
Background Error processing and inhibitory control enable the adjustment of behaviors to
meet task demands. Functional magnetic resonance imaging studies report brain activation …
meet task demands. Functional magnetic resonance imaging studies report brain activation …
Deficits in conditioned fear extinction in obsessive-compulsive disorder and neurobiological changes in the fear circuit
Importance Obsessive-compulsive disorder (OCD) may be characterized by impaired self-
regulation and behavioral inhibition. Elevated fear and anxiety are common characteristics …
regulation and behavioral inhibition. Elevated fear and anxiety are common characteristics …