[HTML][HTML] Modification of the surface nanotopography of implant devices: A translational perspective

K Harawaza, B Cousins, P Roach, A Fernandez - Materials Today Bio, 2021 - Elsevier
There is an increasing need for the development of superior, safe, and more sophisticated
implants, especially as our society historically has been moving towards an increasingly …

Development of novel, value-based, digital endpoints for clinical trials: a structured approach toward fit-for-purpose validation

MD Kruizinga, FE Stuurman, V Exadaktylos… - Pharmacological …, 2020 - ASPET
Novel digital endpoints gathered via wearables, small devices, or algorithms hold great
promise for clinical trials. However, implementation has been slow because of a lack of …

Expectations and attitudes towards medical artificial intelligence: A qualitative study in the field of stroke

J Amann, E Vayena, KE Ormond, D Frey, VI Madai… - Plos one, 2023 - journals.plos.org
Introduction Artificial intelligence (AI) has the potential to transform clinical decision-making
as we know it. Powered by sophisticated machine learning algorithms, clinical decision …

Embedded sensor systems in medical devices: Requisites and challenges ahead

N Arandia, JI Garate, J Mabe - Sensors, 2022 - mdpi.com
The evolution of technology enables the design of smarter medical devices. Embedded
Sensor Systems play an important role, both in monitoring and diagnostic devices for …

Emerging Raman spectroscopy and saliva-based diagnostics: from challenges to applications

E Buchan, M Hardy, PC Gomes, L Kelleher… - Applied Spectroscopy …, 2024 - Taylor & Francis
The study of salivary manifestation of various health disorders via Raman spectroscopy, as a
noninvasive molecular sensing technique to analyze molecular signatures in the saliva …

Not all nebulizers are created equal: Considerations in choosing a nebulizer for aerosol delivery during mechanical ventilation

R MacLoughlin, I Martin-Loeches - Expert Review of Respiratory …, 2023 - Taylor & Francis
Introduction Aerosol therapy is commonly prescribed in the mechanically ventilated patient.
Jet nebulizers (JN) and vibrating mesh nebulizers (VMN) are the most common nebulizer …

Beyond the RCT: when are randomized trials unnecessary for new therapeutic devices, and what should we do instead?

A Páez, M Rovers, K Hutchison, W Rogers… - Annals of …, 2022 - journals.lww.com
Objective: The aim of this study was to develop an evidence-based framework for evaluation
of therapeutic devices, based on ethical principles and clinical evidence considerations …

Shaping the future of cardiovascular medicine in the new era of wearable devices

S Gehr, C Russmann - Nature Reviews Cardiology, 2022 - nature.com
Wearable devices are widely used and have a high level of societal acceptance, opening
unimagined and unexploited possibilities in cardiovascular medicine. In this Clinical …

Preparing healthcare, academic institutions, and notified bodies for their involvement in the innovation of medical devices under the new European regulation

F Garzotto, RI Comoretto, L Dorigo… - Expert Review of …, 2022 - Taylor & Francis
Introduction Favoring innovation by making timely medical technology available to people
and by securing patients' safety is a challenge. Areas covered The new European Medical …

[HTML][HTML] Improving maternal safety: Usability and performance assessment of a new medical device for the treatment of postpartum haemorrhage

S Candidori, N Dozio, K Osouli, S Graziosi, AA Zanini… - Applied Ergonomics, 2024 - Elsevier
Postpartum haemorrhage (PPH) is an obstetric emergency causing nearly one-quarter of
maternal deaths worldwide, 99% of these in low-resource settings (LRSs). Uterine balloon …