The differential diagnosis of differences or disorders of sex development (DSD) belongs to
the most complex fields in medicine. It requires a multidisciplinary team conducting a …

Differences/disorders of sex development (DSD) are a heterogeneous group of congenital
conditions that result in discordance between an individual's sex chromosomes, gonads …

It is paramount that any child or adolescent with a suspected difference or disorder of sex
development (DSD) is assessed by an experienced clinician with adequate knowledge …

Abstract An Endo-European Reference Network guideline initiative was launched including
16 clinicians experienced in endocrinology, pediatric and adult and 2 patient …

Aims Hypogonadism is associated with cardiovascular disease. However, the
cardiovascular impact of hypogonadism during development is unknown. Using …

Abstract Context Steroidogenic factor 1 (NR5A1/SF-1) is a nuclear receptor that regulates
sex development, steroidogenesis, and reproduction. Genetic variants in NR5A1/SF-1 are …

Background: Despite distinct underlying aetiologies, the clinical phenotypes and hormonal
profiles of children with various differences of sex development (DSD) are often similar …

Reaching a firm diagnosis is vital for the long-term management of a patient with a
difference or disorder of sex development (DSD). This is especially the case in XY DSD …

The International Disorders of Sex Development (I-DSD) and International Congenital
Adrenal Hyperplasia registry (I-CAH) Registries were originally developed over 10 years …

Although the outcome of hypospadias surgery requires careful scrutiny, there is little
consensus on what clinical outcome parameters should be considered essential as part of …