RNA-binding proteins (RBPs) are key components in RNA metabolism, regulating the
temporal, spatial and functional dynamics of RNAs. Altering the expression of RBPs has …

The list of developmental and degenerative diseases that are caused by expansion of
unstable repeats continues to grow, and is now approaching 20 disorders. The pathogenic …

Fragile X-associated tremor/ataxia syndrome (FXTAS) is an adult-onset neurodegenerative
disorder that affects carriers, principally males, of premutation alleles (55–200 CGG repeats) …

Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder
caused by expansion of 55–200 CGG repeats in the 5′‐UTR of the FMR1 gene. FXTAS is …

Abstract Myotonic dystrophy type 1 (DM1) is caused by a CTG expansion mutation located in
the 3′ untranslated portion of the dystrophica myotonin protein kinase gene. The …

Fragile X syndrome is the most common form of inherited mental retardation. The disorder is
mainly caused by the expansion of the trinucleotide sequence CGG located in the 5′ UTR …

Disorders characterized by expansion of an unstable nucleotide repeat account for a
number of inherited neurological diseases. Here, we review examples of unstable repeat …

Fragile X syndrome (FXS) is caused by a full mutation expansion (> 200 CGG repeats) in the
FMR1 gene that results in a deficiency of the fragile X mental retardation protein. Although …

Fragile X‐associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder with
core features of action tremor and cerebellar gait ataxia. Frequent associated findings …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder defined by altered social
interaction and communication, and repetitive, restricted, inflexible behaviors. Approximately …