Current status on the development of pseudoviruses for enveloped viruses

Q Li, Q Liu, W Huang, X Li… - Reviews in medical …, 2018 - Wiley Online Library
Emerging and reemerging infectious diseases have a strong negative impact on public
health. However, because many of these pathogens must be handled in biosafety level, 3 or …

Longitudinal observation and decline of neutralizing antibody responses in the three months following SARS-CoV-2 infection in humans

J Seow, C Graham, B Merrick, S Acors, S Pickering… - Nature …, 2020 - nature.com
Antibody responses to SARS-CoV-2 can be detected in most infected individuals 10–15 d
after the onset of COVID-19 symptoms. However, due to the recent emergence of SARS …

Peripheral immunophenotypes in children with multisystem inflammatory syndrome associated with SARS-CoV-2 infection

MJ Carter, M Fish, A Jennings, KJ Doores, P Wellman… - Nature medicine, 2020 - nature.com
Recent reports highlight a new clinical syndrome in children related to severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)—multisystem inflammatory syndrome in …

Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays

KHD Crawford, R Eguia, AS Dingens, AN Loes… - Viruses, 2020 - mdpi.com
SARS-CoV-2 enters cells using its Spike protein, which is also the main target of neutralizing
antibodies. Therefore, assays to measure how antibodies and sera affect Spike-mediated …

Extremely potent human monoclonal antibodies from COVID-19 convalescent patients

E Andreano, E Nicastri, I Paciello, P Pileri… - Cell, 2021 - cell.com
Human monoclonal antibodies are safe, preventive, and therapeutic tools that can be rapidly
developed to help restore the massive health and economic disruption caused by the …

Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern

L Dupont, LB Snell, C Graham, J Seow, B Merrick… - Nature …, 2021 - nature.com
COVID-19 vaccine design and vaccination rollout need to take into account a detailed
understanding of antibody durability and cross-neutralizing potential against SARS-CoV-2 …

Viral infection neutralization tests: A focus on severe acute respiratory syndrome‐coronavirus‐2 with implications for convalescent plasma therapy

D Focosi, F Maggi, P Mazzetti… - Reviews in medical …, 2021 - Wiley Online Library
Viral neutralization tests (VNTs) have long been considered old‐fashioned tricks in the
armamentarium of fundamental virology, with laboratory implementation for a limited array of …

The polybasic cleavage site in SARS-CoV-2 spike modulates viral sensitivity to type I interferon and IFITM2

H Winstone, MJ Lista, AC Reid, C Bouton… - Journal of …, 2021 - Am Soc Microbiol
The cellular entry of severe acute respiratory syndrome-associated coronaviruses types 1
and 2 (SARS-CoV-1 and-2) requires sequential protease processing of the viral spike …

The green tea catechin epigallocatechin gallate inhibits SARS-CoV-2 infection

L Henss, A Auste, C Schürmann… - Journal of General …, 2021 - microbiologyresearch.org
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has caused a
pandemic with tens of millions of cases and more than a million deaths. The infection causes …

[HTML][HTML] A neutralizing epitope on the SD1 domain of SARS-CoV-2 spike targeted following infection and vaccination

J Seow, H Khan, A Rosa, V Calvaresi, C Graham… - Cell Reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike is the target for
neutralizing antibodies elicited following both infection and vaccination. While extensive …