Epidemiology, presentation, and diagnosis of celiac disease

B Lebwohl, A Rubio-Tapia - Gastroenterology, 2021 - Elsevier
The incidence of celiac disease is increasing, partly because of improved recognition of, and
testing for, the disease. The rise in incidence is also due to a real increase of this immune …

Viruses and autoimmunity: a review on the potential interaction and molecular mechanisms

MK Smatti, FS Cyprian, GK Nasrallah, AA Al Thani… - Viruses, 2019 - mdpi.com
For a long time, viruses have been shown to modify the clinical picture of several
autoimmune diseases, including type 1 diabetes (T1D), systemic lupus erythematosus …

Coeliac disease

K Lindfors, C Ciacci, K Kurppa, KEA Lundin… - Nature reviews Disease …, 2019 - nature.com
Coeliac disease is an immune-mediated enteropathy against dietary gluten present in
wheat, rye and barley and is one of the most common lifelong food-related disorders …

[HTML][HTML] Maternal microbiota, early life colonization and breast milk drive immune development in the newborn

C Kalbermatter, N Fernandez Trigo… - Frontiers in …, 2021 - frontiersin.org
The innate immune system is the oldest protection strategy that is conserved across all
organisms. Although having an unspecific action, it is the first and fastest defense …

Coeliac disease

B Lebwohl, DS Sanders, PHR Green - The Lancet, 2018 - thelancet.com
Coeliac disease occurs in about 1% of people in most populations. Diagnosis rates are
increasing, and this seems to be due to a true rise in incidence rather than increased …

[HTML][HTML] Celiac disease: a review of current concepts in pathogenesis, prevention, and novel therapies

JA Tye-Din, HJ Galipeau, D Agardh - Frontiers in pediatrics, 2018 - frontiersin.org
Our understanding of celiac disease and how it develops has evolved significantly over the
last half century. Although traditionally viewed as a pediatric illness characterized by …

Current and emerging therapies for coeliac disease

L Kivelä, A Caminero, DA Leffler… - Nature reviews …, 2021 - nature.com
Coeliac disease is a common enteropathy that occurs in genetically susceptible individuals
in response to the ingestion of gluten proteins present in wheat, rye and barley. Currently …

Celiac disease and the microbiome

F Valitutti, S Cucchiara, A Fasano - Nutrients, 2019 - mdpi.com
Growing evidence supports the hypothesis that changes in both the composition and
function of the intestinal microbiome are associated with a number of chronic inflammatory …

Association of gluten intake during the first 5 years of life with incidence of celiac disease autoimmunity and celiac disease among children at increased risk

CA Aronsson, HS Lee, EMH af Segerstad, U Uusitalo… - Jama, 2019 - jamanetwork.com
Importance High gluten intake during childhood may confer risk of celiac disease. Objectives
To investigate if the amount of gluten intake is associated with celiac disease autoimmunity …

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

A Caminero, JL McCarville, HJ Galipeau… - Nature …, 2019 - nature.com
Microbe-host interactions are generally homeostatic, but when dysfunctional, they can incite
food sensitivities and chronic diseases. Celiac disease (CeD) is a food sensitivity …