The innate immune system responds in a rapid and non‐specific manner against
immunologic threats; inflammation is part of this response. This is followed by a slower but …

The phagocytic response of innate immune cells such as macrophages is defined by the
activation of complex signaling networks that are stimulated by microbial contact. Many …

The carbohydrate polymers known as β-1, 3-d-glucans exert potent effects on the immune
system—stimulating antitumour and antimicrobial activity, for example—by binding to …

Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
industrialized nations, affecting 30–50 million people worldwide. The earliest clinical …

We recently identified dectin-1 (βGR) as a major β-glucan receptor on leukocytes and
demonstrated that it played a significant role in the non-opsonic recognition of soluble and …

Nowadays macrofungi are distinguished as important natural resources of
immunomodulating and anticancer agents and with regard to the increase in diseases …

We have examined macrophage receptors that mediate phagocytosis of virulent strains
(Erdman and H37Rv) and an attenuated strain (H37Ra) of the intracellular pathogen …

Apoptotic cells are rapidly engulfed by phagocytes, but the receptors and ligands
responsible for this phenomenon are incompletely characterized. Previously described …

Mammalian cell receptors that promote entry of intracellular bacteria into nonphagocytic
cells have not been identified. We show here that multiple members of the integrin …

Post-traumatic cystic cavitation, in which the size and severity of a CNS injury progress from
a small area of direct trauma to a greatly enlarged secondary injury surrounded by glial scar …