Background: Pulsed radiofrequency (PRF) treatment uses low energy, short pulsations to
modulate tissue characteristics. PRF treatment has been effective as an interventional pain …

Background The molecular mechanism of pulsed radiofrequency (PRF) in chronic pain
management is not fully understood. Chronic pain involves the activation of specific N …

Objective: Our previous study found that astrocytes are involved in cumulative analgesia;
however, the underlying mechanism remains unclear. The aim of this study was to further …

Diabetic neuropathic pain is one of the most common complications of diabetes.
Mechanisms underlying the central modulation are still unclear. Here, we investigated the …

Important roles in the initiation and maintenance of postoperative pain are played by the
functional control of kainate (KA) and α-amino-3-hydroxy-5-methyl-4-isoxazole propionate …

Background Herpes zoster (HZ)‐related pain, characterized by chronic and persistent pain
with a dermatomal distribution, is a relatively common complication of HZ. Pulsed …

To explore the role of melatonin in the mechanism of remifentanil-induced hyperalgesia in
rats by improving the plasticity of neuronal dendritic spines. Purchase 30 SD rats (175~ 200 …

Objective To investigate the glial cell and AMPA (alpha-amino-3-hydroxy-5-methyl-4-
isoxazolepropionic acid) receptor activity after surgery for disc herniation pain model …

Background: To our knowledge, there have been no published clinical trials to assess the
synergistic effects of applying pulsed radiofrequency (PRF) stimulation of the suprascapular …

Radicular pain due to spinal degeneration is commonly managed with transforaminal
epidural steroid injections (TFESI) to reduce inflammation. However, in cases where pain …