Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis
A Khan, MA Markus, A Svetlove, S Hülsmann… - Scientific Reports, 2023 - nature.com
Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung,
which is associated with different lung disease. Treatment options are still sparse …
which is associated with different lung disease. Treatment options are still sparse …
[HTML][HTML] Semi-automated micro-computed tomography lung segmentation and analysis in mouse models
Computed Tomography (CT) is a standard clinical tool utilized to diagnose known lung
pathologies based on established grading methods. However, for preclinical trials and …
pathologies based on established grading methods. However, for preclinical trials and …
Monitoring the response to Nintedanib treatment in a mouse model of lung fibrosis using longitudinal X-ray based lung function measurement
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive, incurable, and
debilitating fibrotic disease. Nintedanib–an oral tyrosine kinase inhibitor–significantly slows …
debilitating fibrotic disease. Nintedanib–an oral tyrosine kinase inhibitor–significantly slows …