Cocaine is the leading cause for drug–abuse-related visits to emergency departments, most
of which are due to cardiovascular complaints. Through its diverse pathophysiological …

The use of cocaine has evolved from chewing the leaves of the Erythroxylon coca bush
thousands of years ago, to purification of cocaine hydrochloride over 100 years ago and its …

Dr. Stoelting's best-selling and highly acclaimed text, Pharmacology and Physiology in
Anesthetic Practice, is now in its thoroughly updated Fourth Edition. In 60 concise, clearly …

The deaths of several celebrities in recent years in association with the nontherapeutic use
of cocaine have focused widespread attention on the problem of cocaine abuse. In 1999, an …

Conclusions...... 1025 V. Hospital Discharge and Post–Hospital Discharge Care...... 1025 A.
Medical Regimen...... 1026 1. Long-Term Medical Therapy...... 1026 B. Postdischarge Follow …

Methods The Writing Committee conducted a comprehensive search of the medical
literature concerning cocaine-associated chest pain and MI. The literature search included …

Cocaine is a powerful stimulant of the sympathetic nervous system by inhibiting
catecholamine reuptake, stimulating central sympathetic outflow, and increasing the …

Cocaine, a powerful vasoconstrictor, induces immune responses including cytokine
elevations. Chronic cocaine use is associated with functional brain impairments potentially …

Evidence for triggering has been summarized previously4, 13 and is based on the following
points. First, MI results from plaque rupture or erosion and thrombosis. 2 Second, thrombotic …

The complications of failure, neural injury and local anaesthetic toxicity are common to all
regional anaesthetic techniques, and individual techniques are associated with specific …