Inter-individual human variability, driven by various genetic and environmental factors,
complicates the ability to develop effective population-based early disease detection …

Functional gastrointestinal disorders (FGIDs), chronic disorders characterized by either
abdominal pain, altered intestinal motility, or their combination, have a worldwide …

Objective To appraise the evidence that pathophysiological mechanisms and individualised
treatment directed at those mechanisms provide an alternative approach to the treatment of …

Current treatments for chronic diarrhea have limited efficacy and several side effects.
Probiotics have the potential to alleviate symptoms of diarrhea. This randomized, double …

The low FODMAP (fermentable oligosaccharide, disaccharide, monosaccharide, and polyol)
diet is a beneficial therapeutic approach for patients with irritable bowel syndrome (IBS) …

Celiac disease (CeD) is a chronic immune-mediated condition triggered by gluten
consumption in genetically predisposed individuals. Approximately 1% of the general …

Summary Background Irritable Bowel Syndrome (IBS) is a functional gastrointestinal
disorder which affects a great number of patients globally. Clinical trials and meta-analyses …

Most adverse reactions to food are patient self-reported and not based on validated tests but
nevertheless lead to dietary restrictions, with patients believing that these restrictions will …

Background Bile acid diarrhoea is a common but overlooked cause of chronic watery
diarrhoea. Plasma 7α-hydroxy-4-cholesten-3-one (C4) is an alternative to the gold standard …

Background: Disorders of gut–brain interaction (DGBIs) have a complex pathophysiology
that is often characterized by a relationship between food ingestion and triggering of …