Gene expression modulation of lipid and central energetic metabolism related genes by high-fat diet intake in the main homeostatic tissues

B Reynés, M Palou, A Palou - Food & function, 2017 - pubs.rsc.org
It is generally assumed that high-fat (HF) diets induce characteristic gene expression
regulation, which may cause metabolic alterations associated with an increased risk of …

Impact of physical exercise on visceral adipose tissue fatty acid profile and inflammation in response to a high-fat diet regimen

S Rocha-Rodrigues, A Rodríguez, IO Gonçalves… - The international journal …, 2017 - Elsevier
Purpose Studies associate specific fatty-acids (FA) with the pathophysiology of inflammation.
We aimed to analyze the impact of exercise on adipose tissue FA profile in response to a …

Long-term intake of a high-protein diet increases liver triacylglycerol deposition pathways and hepatic signs of injury in rats

R Díaz-Rúa, J Keijer, A Palou… - The Journal of nutritional …, 2017 - Elsevier
Intake of high-protein (HP) diets has increased over the last years, mainly due to their
popularity for body weight control. Liver is the main organ handling ingested macronutrients …

Maternal consumption of a cafeteria diet during lactation in rats leads the offspring to a thin-outside-fat-inside phenotype

CA Pomar, R Van Nes, J Sánchez, C Picó… - International Journal of …, 2017 - nature.com
Methods: Nursing rats were fed a control diet or a cafeteria diet during lactation. Milk was
obtained at different time points of lactation. Offspring (males and females) were weaned …

Neandertals' large lower thorax may represent adaptation to high protein diet

M Ben‐Dor, A Gopher, R Barkai - American journal of physical …, 2016 - Wiley Online Library
Humans are limited in their capacity to convert protein into energy. We present a hypothesis
that a “bell” shaped thorax and a wide pelvis evolved in Neandertals, at least in part, as an …

Peripheral blood mononuclear cells as a source to detect markers of homeostatic alterations caused by the intake of diets with an unbalanced macronutrient …

R Díaz-Rúa, J Keijer, A Caimari… - The Journal of nutritional …, 2015 - Elsevier
Peripheral blood mononuclear cells (PBMCs) are accessible in humans, and their gene
expression pattern was shown to reflect overall physiological response of the body to a …

Oral leptin supplementation throughout lactation in rats prevents later metabolic alterations caused by gestational calorie restriction

N Szostaczuk, T Priego, M Palou, A Palou… - International Journal of …, 2017 - nature.com
Objectives: Calorie-restriction during gestation in rats has been seen to produce lasting
detrimental effects in the offspring, affecting energy balance control and other related …

Effects of endurance training on autophagy and apoptotic signaling in visceral adipose tissue of prolonged high fat diet-fed rats

S Rocha-Rodrigues, IO Gonçalves, J Beleza… - European journal of …, 2018 - Springer
Purpose Autophagy and apoptosis play critical roles in both development and tissue
homeostasis in response to (patho) physiological stimuli, such as high-fat diet (HFD) and …

Cpt1a gene expression in peripheral blood mononuclear cells as an early biomarker of diet-related metabolic alterations

R Díaz-Rúa, A Palou, P Oliver - Food & nutrition research, 2016 - Taylor & Francis
Background Research on biomarkers that provide early information about the development
of future metabolic alterations is an emerging discipline. Gene expression analysis in …

Effects of dietary fatty acid composition on lipid metabolism and body fat accumulation in ovariectomized rats

JH Yeh, YT Tung, YS Yeh, YW Chien - Nutrients, 2021 - mdpi.com
Background: Obesity is a state of excess energy storage resulting in body fat accumulation,
and postmenopausal obesity is a rising issue. In this study using ovariectomized (OVX) rats …