Deciphering the relationship between SARS-CoV-2 and cancer

M Costanzo, MAR De Giglio, GN Roviello - International Journal of …, 2023 - mdpi.com
Some viruses are known to be associated with the onset of specific cancers. These
microorganisms, oncogenic viruses or oncoviruses, can convert normal cells into cancer …

Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

Complement factor D targeting protects endotheliopathy in organoid and monkey models of COVID-19

E Kawakami, N Saiki, Y Yoneyama, C Moriya… - Cell Stem Cell, 2023 - cell.com
COVID-19 is linked to endotheliopathy and coagulopathy, which can result in multi-organ
failure. The mechanisms causing endothelial damage due to severe acute respiratory …

Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 syndrome with and without postural orthostatic tachycardia …

A Mahdi, A Zhao, E Fredengren, A Fedorowski… - Scientific Reports, 2023 - nature.com
Abstract Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction,
especially postural orthostatic tachycardia syndrome (POTS). Patients with PACS, both in …

Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction

S Lodge, NG Lawler, N Gray, R Masuda… - International Journal of …, 2023 - mdpi.com
An integrative multi-modal metabolic phenotyping model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …

Identification of key genes associated with persistent immune changes and secondary immune activation responses induced by influenza vaccination after COVID-19 …

J Ren, XC Zhou, K Huang, L Chen, W Guo… - Computers in Biology …, 2024 - Elsevier
COVID-19 is hypothesized to exert enduring effects on the immune systems of patients,
leading to alterations in immune-related gene expression. This study aimed to scrutinize the …

Combining semi-targeted metabolomics and machine learning to identify metabolic alterations in the serum and urine of hospitalized patients with COVID-19

G Baiges-Gaya, S Iftimie, H Castañé… - Biomolecules, 2023 - mdpi.com
Viral infections cause metabolic dysregulation in the infected organism. The present study
used metabolomics techniques and machine learning algorithms to retrospectively analyze …

The role of peroxisome proliferator-activated receptors in the modulation of hyperinflammation induced by SARS-CoV-2 infection: A perspective for COVID-19 therapy

A Hasankhani, A Bahrami, B Tavakoli-Far… - Frontiers in …, 2023 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a severe respiratory disease caused by infection
with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that affects the lower …

Dysregulation of glutamine/glutamate metabolism in COVID‐19 patients: A metabolism study in African population and mini meta‐analysis

X Li, B Tu, XA Zhang, W Xu, J Chen… - Journal of Medical …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) remains a serious global threat. The
metabolic analysis had been successfully applied in the efforts to uncover the pathological …

COVID-19 and one-carbon metabolism

J Perła-Kaján, H Jakubowski - International journal of molecular sciences, 2022 - mdpi.com
Dysregulation of one-carbon metabolism affects a wide range of biological processes and is
associated with a number of diseases, including cardiovascular disease, dementia, neural …