Schizophrenia is a severe psychiatric disorder affecting up to 1% of the worldwide population. Available therapy presents different limits comprising lack of efficiency in …
P Chen, W Zhao, Y Guo, J Xu… - BioMed research …, 2016 - Wiley Online Library
CX3C chemokine ligand 1 (CX3CL1) is an intriguing chemokine belonging to the CX3C family. CX3CL1 is secreted by neurons and plays an important role in modulating glial …
SA El-Marasy, RM Abd-Elsalam… - … Macedonian journal of …, 2018 - ncbi.nlm.nih.gov
AIM: This study aims to elucidate the possible ameliorative effect of silymarin on scopolamine-induced dementia using the object recognition test (ORT) in rats. METHODS …
Microglia are the immune effector cells of the central nervous system (CNS) and react to pathologic events with a complex process including the release of nitric oxide (NO). NO is a …
Close to 19% of the world population suffers from anxiety. Current medications for this chronic mental disorder have improved treatment over the last half century or more, but the …
VO Ivanova, PM Balaban, NV Bal - International Journal of Molecular …, 2020 - mdpi.com
Nitric oxide (NO) is a gaseous molecule with a large number of functions in living tissue. In the brain, NO participates in numerous intracellular mechanisms, including synaptic …
UT Yilmazer, B Pehlivan, S Guney… - Behavioural Brain …, 2024 - Elsevier
Abstract Alzheimer's disease (AD), the most frequent neurodegenerative disease within dementias, affects the CNS, leading to gradual memory issues and cognitive dysfunction …
RAM Serafim, FG Pernichelle… - Expert Opinion on Drug …, 2017 - Taylor & Francis
Introduction: There is a great interest in Nitric oxide (NO) within medicinal chemistry since it's involved in human signaling pathways. Prodrugs or hybrid compounds containing NO-donor …
This study examined the modulatory effect of Black nightshade (Solanum nigrum L) and African eggplant (Solanum macrocarpon L) leaves on cognitive function, antioxidant status …