Effect of heavy metals: An overview

R Bharti, R Sharma - Materials Today: Proceedings, 2022 - Elsevier
Recently, environmental pollution has become a serious concern worldwide. In this modern
era, more Urbanization and Industrialization have led to the wide distribution of pollutants …

The role of environmental exposures in neurodegeneration and neurodegenerative diseases

JR Cannon, JT Greenamyre - Toxicological Sciences, 2011 - academic.oup.com
Neurodegeneration describes the loss of neuronal structure and function. Numerous
neurodegenerative diseases are associated with neurodegeneration. Many are rare and …

Multifaceted effects of aluminium in neurodegenerative diseases: A review

S Maya, T Prakash, KD Madhu, D Goli - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Aluminium (Al) is the most common metal and widely distributed in our environment. Al was
first isolated as an element in 1827, and its use began only after 1886. Al is widely used for …

Neurotoxic effects of aluminium exposure as a potential risk factor for Alzheimer's disease

M Dey, RK Singh - Pharmacological Reports, 2022 - Springer
Aluminium is one of the most widely distributed elements of the Earth's crust. Its routine use
has resulted in excessive human exposure and due to the potential neurotoxic effects has …

Oxidative stress and mitochondrial dysfunction in aluminium neurotoxicity and its amelioration: a review

V Kumar, KD Gill - Neurotoxicology, 2014 - Elsevier
Aluminium is light weight and toxic metal present ubiquitously on earth which has gained
considerable attention due to its neurotoxic effects. The widespread use of products made …

Is aluminum exposure a risk factor for neurological disorders?

E Inan-Eroglu, A Ayaz - Journal of Research in Medical Sciences, 2018 - journals.lww.com
Aluminum (Al) is widely found in the nature. Although the relation between Al and
neurodegenerative diseases is still controversial, Al is related with many brain diseases …

Aluminum induces neurodegeneration and its toxicity arises from increased iron accumulation and reactive oxygen species (ROS) production

Z Wu, Y Du, H Xue, Y Wu, B Zhou - Neurobiology of aging, 2012 - Elsevier
The neurotoxicity of aluminum (Al)− the most abundant metal element on earth− has been
known for years. However, the mechanism of Al-induced neurodegeneration and its …

Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-β stability, oligomerization, and aggregation: amyloid-β destabilization promotes annular protofibril formation

WT Chen, YH Liao, HM Yu, IH Cheng… - Journal of Biological …, 2011 - ASBMB
Abnormally high concentrations of Zn 2+, Cu 2+, and Fe 3+ are present along with amyloid-β
(Aβ) in the senile plaques in Alzheimer disease, where Al 3+ is also detected. Aβ …

Pro-oxidant activity of aluminum: promoting the Fenton reaction by reducing Fe (III) to Fe (II)

F Ruipérez, JI Mujika, JM Ugalde, C Exley… - Journal of inorganic …, 2012 - Elsevier
The possibility for an Al-superoxide complex to reduce Fe (III) to Fe (II), promoting oxidative
damage through the Fenton reaction, is investigated using highly accurate ab initio methods …

[HTML][HTML] Arsenic, cadmium, lead, and aluminium concentrations in human milk at early stages of lactation

HH Chao, CH Guo, CB Huang, PC Chen, HC Li… - Pediatrics & …, 2014 - Elsevier
Background Human milk is considered to be the best nutrition for all infants because it
provides the optimal source of nutritional, immunological, developmental, psychological …