Neurodegenerative disorders of the eye and of the brain: a perspective on their fluid-dynamical connections and the potential of mechanism-driven modeling
Neurodegenerative disorders (NDD) such as Alzheimer's and Parkinson's diseases are
significant causes of morbidity and mortality worldwide. The pathophysiology of NDD is still …
significant causes of morbidity and mortality worldwide. The pathophysiology of NDD is still …
[图书][B] Ocular fluid dynamics: anatomy, physiology, imaging techniques, and mathematical modeling
The book aims at providing an overview of the current theoretical approaches available to
model ocular fluid-dynamics in health and disease, along with the outstanding questions in …
model ocular fluid-dynamics in health and disease, along with the outstanding questions in …
Mathematical Modelling and Simulations of the Hemodynamics in the eye
MCM Aletti - 2017 - theses.hal.science
The structure of the eye offers a unique opportunity to directly observe the microcirculation,
by means, for instance, of fundus camera, which are cheap devices commonly used in the …
by means, for instance, of fundus camera, which are cheap devices commonly used in the …
A stabilized dual mixed hybrid finite element method with lagrange multipliers for three-dimensional elliptic problems with internal interfaces
R Sacco, AG Mauri, G Guidoboni - Journal of Scientific Computing, 2020 - Springer
This work studies an elliptic boundary value problem with diffusive, advective and reactive
terms, in a three-dimensional domain composed of two media separated by a selective …
terms, in a three-dimensional domain composed of two media separated by a selective …
A theoretical approach for the electrochemical characterization of ciliary epithelium
The ciliary epithelium (CE) is the primary site of aqueous humor (AH) production, which
results from the combined action of ultrafiltration and ionic secretion. Modulation of ionic …
results from the combined action of ultrafiltration and ionic secretion. Modulation of ionic …
Mathematical models of aqueous production, flow and drainage
The aqueous humour (AH) is a transparent fluid with water-like properties that fills the
anterior chamber (AC, the region between the cornea and the iris) and the posterior …
anterior chamber (AC, the region between the cornea and the iris) and the posterior …
Mathematical modeling for novel treatment approaches to open-angle glaucoma
Introduction: Reduction of intraocular pressure, the only currently approved therapy for Open-
angle glaucoma (OAG), has yet to fully arrest the disease process in many individuals …
angle glaucoma (OAG), has yet to fully arrest the disease process in many individuals …
A theoretical study of aqueous humor secretion based on a continuum model coupling electrochemical and fluid-dynamical transmembrane mechanisms
Intraocular pressure, resulting from the balance of aqueous humor (AH) production and
drainage, is the only approved treatable risk factor in glaucoma. AH production is …
drainage, is the only approved treatable risk factor in glaucoma. AH production is …
Anatomy and Physiology of the Anterior Chamber: Impact on Product Development
SP Srinivas, G Guidoboni, A Burli, B Harjai… - … : From Bench to Bedside, 2022 - Springer
Ophthalmic drugs are administered as drops on the ocular surface because of simplicity,
although they are lost to the nasolacrimal duct rapidly (half-life at the ocular surface is small …
although they are lost to the nasolacrimal duct rapidly (half-life at the ocular surface is small …
Mathematical modeling, analysis and simulations for fluid mechanics and their relevance to in silico medicine
M Szopos - 2017 - theses.hal.science
This manuscript gathers my contributions focused on developing new mathematical and
computational methods for analyzing biological flows as complex multiphysics and …
computational methods for analyzing biological flows as complex multiphysics and …