The problem of inadequate statistical reporting is long standing and widespread in the
biomedical literature, including in cardiovascular physiology. Although guidelines for …

Nicotinamide adenine dinucleotide (NAD+) and related metabolites are central mediators of
fuel oxidation and bioenergetics within cardiomyocytes. Additionally, NAD+ is required for …

The nicotinamide adenine dinucleotide (NAD+) is an essential redox cofactor, involved in
various physiological and molecular processes, including energy metabolism, epigenetics …

In addition to its central role in mediating oxidation reduction in fuel metabolism and
bioenergetics, nicotinamide adenine dinucleotide (NAD+) has emerged as a vital co …

Excitable cells of the nervous and cardiovascular systems depend on an assortment of
plasmalemmal potassium channels to control diverse cellular functions. Voltage-gated …

Adequate oxygen delivery to the heart during stress is essential for sustaining cardiac
function. Acute increases in myocardial oxygen demand evoke coronary vasodilation and …

Voltage-gated potassium (Kv) channels control myocardial repolarization. Pore-forming Kvα
proteins associate with intracellular Kvβ subunits, which bind pyridine nucleotides with high …

The use of nanoparticles (NPs) has emerged as a potential tool for safe and effective drug
delivery. In the present study, we developed small molecule P7C3-based NPs and tested its …

Voltage-gated potassium (Kv) channels play an essential role in the regulation of membrane
excitability and thereby control physiological processes such as cardiac excitability, neural …

Background Diabetic (DM) inactivation of small conductance calcium-activated potassium
(SK) channels contributes to coronary endothelial dysfunction. However, the mechanisms …