Numerous light-based diagnostic and therapeutic devices are routinely used in the clinic.
These devices have a familiar look as items plugged in the wall or placed at patients' …

The variety of physiological functions controlled by dopamine in the brain and periphery is
mediated by the D 1, D 2, D 3, D 4 and D 5 dopamine GPCRs. Drugs acting on dopamine …

The discovery in 2001 of a G protein-coupled receptor family, subsequently termed trace
amine-associated receptors (TAAR), triggered a resurgence of interest in so-called trace …

Electronic nose (enose, EN) and electronic tongue (etongue, ET) have been designed to
simulate human senses of smell and taste in the best possible way. The signals acquired …

Recent advances in the development of fluorescent ligands for G-protein-coupled receptors
(GPCRs) and receptor tyrosine kinase receptors (RTKs) have facilitated the study of these …

Resonance energy transfer technologies have achieved great success in the field of
analysis. Particularly, fluorescence resonance energy transfer (FRET) and bioluminescence …

GPCRs are the largest receptor family that are involved in virtually all biological processes.
Pharmacologically, they are highly druggable targets, as they cover more than 40% of all …

Signal transduction processes in living organisms are mainly transmitted through
conformational changes in transmembrane protein receptors. So far, the development of …

Proteinase-activated receptors (PARs) are G protein–coupled receptors that transmit cellular
responses to extracellular proteases and have important functions in vascular physiology …

Biosensors are devices that are capable of detecting specific biological analytes and
converting their presence or concentration into some electrical, thermal, optical or other …