With the continuous improvement of human technology, the medical field has gradually
moved from molecular therapy to cellular therapy. As a safe and effective therapeutic tool …

Hydrogels prepared from natural polymer have attracted extensive attention in biomedical
fields such as drug delivery, wound healing, and regenerative medicine due to their good …

Mesenchymal stem cell (MSC) chondrogenesis in three-dimensional (3D) culture involves
dynamic changes in cytoskeleton architecture during mesenchymal condensation before …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

Biofabrication is providing scientists and clinicians the ability to produce engineered tissues
with desired shapes and gradients of composition and biological cues. Typical resolutions …

While injectable in situ cross-linking collagen hydrogels offer great potential for applying
stem cell therapy to regenerate articular cartilage via minimally invasive procedures, the …

Mesenchymal stem cells (MSCs) interact with their surroundings via integrins, which link to
the actin cytoskeleton and translate physical cues into biochemical signals through …

Articular cartilage consists of hyaline cartilage, is a major constituent of the human
musculoskeletal system and has critical functions in frictionless joint movement and articular …

We performed a comparative study of the proliferative potential of human mesenchymal
stromal cells (MSC) from three sources (tooth pulp, adipose tissue, and Wharton's jelly) in …

Achieving chondrogenic differentiation of bone marrow mesenchymal stem cells (BMSCs)
successfully is crucial for cartilage regeneration. To date, various hydrogels with different …