Cancer is the second leading cause of death globally, trailing only heart disease. In the
United States alone, 1.9 million new cancer cases and 609,360 deaths were recorded for …

In the dynamic landscape of targeted therapeutics, drug discovery has pivoted towards
understanding underlying disease mechanisms, placing a strong emphasis on molecular …

Since ancient times, Moringa oleifera has been a common vegetable in many nations. It has
a large number of phenolic compounds with a diverse range of biological activity. It has …

Motivation Many approaches in systems biology have been applied in drug repositioning
due to the increased availability of the omics data and computational biology tools. Using a …

Breast cancer remains a major public health challenge worldwide. The identification of
accurate biomarkers is critical for the early detection and effective treatment of breast cancer …

Background The mechanisms by which SLC2A1 enhances chemo-resistance of taxanes to
non-small cell lung cancer (NSCLC) remains enigmatic. Methods An investigation into the …

Non-small cell lung cancer (NSCLC) is a type of lung cancer associated with translocation of
the EML4 and ALK genes on the short arm of chromosome 2. This leads to the development …

Pancreatic cancer, a malignancy notorious for its late-stage diagnosis and low patient
survival rates, remains a formidable global health challenge. The currently available FDA …

Background Preclinical evidence suggests that certain antipsychotic medications may inhibit
the development of lung cancer. This study aims to investigate the association between …

Colorectal cancer (CRC) is a major worldwide health issue, with high rates of both
occurrence and mortality. Dysregulation of the transforming growth factor-beta (TGF-β) …