[HTML][HTML] Relationship between amyloid-β deposition and blood–brain barrier dysfunction in Alzheimer's disease

D Wang, F Chen, Z Han, Z Yin, X Ge… - Frontiers in Cellular …, 2021 - frontiersin.org
Amyloid-β (Aβ) is the predominant pathologic protein in Alzheimer's disease (AD). The
production and deposition of Aβ are important factors affecting AD progression and …

Interactions between glial cells and the blood-brain barrier and their role in Alzheimer's disease

M Zhao, XF Jiang, HQ Zhang, JH Sun, H Pei… - Ageing research …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), which is an irreversible neurodegenerative disorder
characterized by senile plaques and neurofibrillary tangles, is the most common form of …

Neurovascular dysfunction and vascular amyloid accumulation as early events in Alzheimer's disease

R Apátiga-Pérez, LO Soto-Rojas… - Metabolic brain …, 2022 - Springer
Alzheimer's disease (AD) is clinically characterized by a progressive loss of cognitive
functions and short-term memory. AD patients present two distinctive neuropathological …

Exploring the therapeutic potential of phytochemicals in Alzheimer's disease: Focus on polyphenols and monoterpenes

I Piccialli, V Tedeschi, L Caputo, S D'Errico… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a chronic, complex neurodegenerative disorder mainly
characterized by the irreversible loss of memory and cognitive functions. Different …

New insights into microglial mechanisms of memory impairment in Alzheimer's disease

N Li, M Deng, G Hu, N Li, H Yuan, Y Zhou - Biomolecules, 2022 - mdpi.com
Alzheimer's disease (AD) is the most common progressive and irreversible
neurodegeneration characterized by the impairment of memory and cognition. Despite years …

Recent mechanisms of neurodegeneration and photobiomodulation in the context of Alzheimer's disease

M Su, D Nizamutdinov, H Liu, JH Huang - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease and the world's primary cause of
dementia, a condition characterized by significant progressive declines in memory and …

[HTML][HTML] Endothelial progenitor cells and vascular alterations in Alzheimer's disease

A Custodia, A Ouro, D Romaus-Sanjurjo… - Frontiers in aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative disease representing the most common
type of dementia worldwide. The early diagnosis of AD is very difficult to achieve due to its …

Neurovascular unit pathology is observed very early in disease progression in the mutant SOD1G93A mouse model of amyotrophic lateral sclerosis

M Yoshikawa, S Aizawa, RW Oppenheim… - Experimental …, 2022 - Elsevier
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease
characterized by motor neuron degeneration that causes neuromuscular denervation …

Thinking outside the black box: are the brain endothelial cells the new main target in Alzheimer's disease?

E Estudillo, A López-Ornelas… - Neural Regeneration …, 2023 - journals.lww.com
The blood-brain barrier is the interface through which the brain interacts with the milieu and
consists mainly of a sophisticated network of brain endothelial cells that forms blood vessels …

Involvement of Astrocytes in the Formation, Maintenance, and Function of the Blood–Brain Barrier

G Schiera, CM Di Liegro, G Schirò, G Sorbello… - Cells, 2024 - mdpi.com
The blood–brain barrier (BBB) is a fundamental structure that protects the composition of the
brain by determining which ions, metabolites, and nutrients are allowed to enter the brain …