[HTML][HTML] Promising influences of caffeic acid and caffeic acid phenethyl ester against natural and chemical toxins: A comprehensive and mechanistic review

S Ehtiati, M Alizadeh, F Farhadi, K Khalatbari… - Journal of Functional …, 2023 - Elsevier
Caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) are natural compounds that have
been found in various foods and plants. These compounds have attracted much attention in …

Caffeic acid phenethyl ester as a protective agent against nephrotoxicity and/or oxidative kidney damage: a detailed systematic review

S Akyol, V Ugurcu, A Altuntas, R Hasgul… - The Scientific World …, 2014 - Wiley Online Library
Caffeic acid phenethyl ester (CAPE), an active component of propolis, has been attracting
the attention of different medical and pharmaceutical disciplines in recent years because of …

In vivo evidences suggesting the role of oxidative stress in pathogenesis of vancomycin-induced nephrotoxicity: protection by erdosteine

F Öktem, MK Arslan, F Ozguner, Ö Candir, HR Yilmaz… - Toxicology, 2005 - Elsevier
The aims of this study were to examine vancomycin (VCM)-induced oxidative stress that
promotes production of reactive oxygen species (ROS) and to investigate the role of …

Thymoquinone supplementation prevents the development of gentamicin‐induced acute renal toxicity in rats

MM Sayed‐Ahmed, MN Nagi - Clinical and Experimental …, 2007 - Wiley Online Library
SUMMARY 1 The present study investigated the possible protective effects of thymoquinone
(TQ), a compound derived from Nigella sativa with strong anti‐oxidant properties, against …

Protective effects of thymoquinone on vancomycin-induced nephrotoxicity in rats

F Basarslan, N Yilmaz, S Ates, T Ozgur… - Human & …, 2012 - journals.sagepub.com
Aim: Oxidative stress has been implicated as a potential responsible mechanism in the
pathogenesis of vancomycin (VCM)-induced renal toxicity. Therefore, we aimed to …

Nigella sativa oil for prevention of chronic cyclosporine nephrotoxicity: an experimental model

E Uz, O Bayrak, E Uz, A Kaya, R Bayrak, B Uz… - American journal of …, 2008 - karger.com
Nephrotoxicity is the main secondary effect of cyclosporine A (CsA) treatment. The
antioxidant action of Nigella sativa oil (NSO) may explain the protective effect of these …

Protective effect of Panax ginseng against serum biochemical changes and apoptosis in kidney of rats treated with gentamicin sulphate

Y Kalkan, KAT Kapakin, A Kara, T Atabay… - Journal of molecular …, 2012 - Springer
The protective effects of Panax ginseng (PG) on gentamicin sulphate (GS) induced acute
nephrotoxicity were investigated in rats. A total of 32 adult Sprague–Dawley rats were …

Protective role of caffeic acid against alcohol‐induced biochemical changes in rats

L Pari, K Karthikesan - Fundamental & clinical pharmacology, 2007 - Wiley Online Library
Caffeic acid is a well‐known phenolic compound mainly present in plants. In this study,
caffeic acid was evaluated for its protective effect against chronic ethanol‐induced …

Protective Effects of Caffeic Acid Phenethyl Ester, Vitamin C, Vitamin E and N‐Acetylcysteine on Vancomycin‐Induced Nephrotoxicity in Rats

S Ocak, S Gorur, S Hakverdi, S Celik… - Basic & clinical …, 2007 - Wiley Online Library
The objective of this study was to compare the beneficial effects of caffeic acid phenethyl
ester (CAPE), vitamin C, vitamin E and N‐acetylcysteine on vancomycin‐induced …

The protective effect of eugenol against gentamicin‐induced nephrotoxicity and oxidative damage in rat kidney

MM Said - Fundamental & clinical pharmacology, 2011 - Wiley Online Library
Gentamicin (GM) is an effective aminoglycoside antibiotic against life‐threatening Gram‐
negative bacteria. However, a major complication of therapeutic doses of GM is …