Automated size selection for short cell-free DNA fragments enriches for circulating tumor DNA and improves error correction during next generation sequencing

S Hellwig, DA Nix, KM Gligorich, JM O'Shea… - PloS one, 2018 - journals.plos.org
Circulating tumor-derived cell-free DNA (ctDNA) enables non-invasive diagnosis,
monitoring, and treatment susceptibility testing in human cancers. However, accurate …

Year-long metagenomic study of river microbiomes across land use and water quality

T Van Rossum, MA Peabody… - Frontiers in …, 2015 - frontiersin.org
Select bacteria, such as Escherichia coli or coliforms, have been widely used as sentinels of
low water quality; however, there are concerns regarding their predictive accuracy for the …

Human activity determines the presence of integron-associated and antibiotic resistance genes in Southwestern British Columbia

MI Uyaguari-Díaz, MA Croxen, Z Luo… - Frontiers in …, 2018 - frontiersin.org
The dissemination of antibiotic resistant bacteria from anthropogenic sources into the
environment poses an emerging public health threat. Antibiotic resistance genes (ARGs) …

Structural, functional, resistome and pathogenicity profiling of the Cooum river

S Aishwarya, K Gunasekaran, PS Kumar, A Begum… - Microbial …, 2021 - Elsevier
The microbial community's structure and functions determine the health, quality, and
anthropogenic conditions of the river ecosystems. The presence of Bacteria such as …

PSORTm: a bacterial and archaeal protein subcellular localization prediction tool for metagenomics data

MA Peabody, WYV Lau, GR Hoad, B Jia… - …, 2020 - academic.oup.com
Motivation Many methods for microbial protein subcellular localization (SCL) prediction
exist; however, none is readily available for analysis of metagenomic sequence data …

Metagenomic investigation of plasma in individuals with ME/CFS highlights the importance of technical controls to elucidate contamination and batch effects

RR Miller, M Uyaguari-Diaz, MN McCabe, V Montoya… - PLoS …, 2016 - journals.plos.org
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease
causing indefinite fatigue. ME/CFS has long been hypothesised to have an infectious cause; …

Characterization of Legionella Species from Watersheds in British Columbia, Canada

MA Peabody, JA Caravas, SS Morrison, JW Mercante… - Msphere, 2017 - Am Soc Microbiol
Legionella spp. present in some human-made water systems can cause Legionnaires'
disease in susceptible individuals. Although legionellae have been isolated from the natural …

Spatiotemporal dynamics of river viruses, bacteria and microeukaryotes

TV Rossum, MI Uyaguari-Diaz, M Vlok, MA Peabody… - bioRxiv, 2018 - biorxiv.org
Freshwater is an essential resource of increasing value, as clean water sources diminish.
Microorganisms in rivers, a major source of renewable freshwater, are significant due to their …

Technologie µLAS pour l'analyse et la purification d'ADN de haut poids moléculaire

N Milon - 2019 - theses.hal.science
Les techniques de séquençage ont connu un extraordinaire développement depuis plus de
40 ans et ont permis une véritable révolution dans le domaine de l'analyse biologique avec …

Antibiotic resistance genes in agriculture and urban influenced watersheds in southwestern British Columbia

MI Uyaguari-Díaz, MA Croxen, Z Luo, KI Cronin… - BioRxiv, 2017 - biorxiv.org
Background The dissemination of antibiotic resistance genes (ARGs) from anthropogenic
activities into the environment poses an emerging public health threat. Water constitutes a …