Progress in the use of dental pulp stem cells in regenerative medicine

E Anitua, M Troya, M Zalduendo - Cytotherapy, 2018 - Elsevier
The field of tissue engineering is emerging as a multidisciplinary area with promising
potential for regenerating new tissues and organs. This approach requires the involvement …

Direct pulp capping: What is the most effective therapy?—Systematic review and meta-analysis

AB Paula, M Laranjo, CM Marto, S Paulo… - Journal of Evidence …, 2018 - Elsevier
Introduction Direct pulp capping therapies use biomaterials to protect exposed tissues,
inducing repair through the production of a mineralized barrier. The purpose of this study …

Dental pulp of the third molar: a new source of pluripotent-like stem cells

M Atari, C Gil-Recio, M Fabregat… - Journal of cell …, 2012 - journals.biologists.com
Dental pulp is particularly interesting in regenerative medicine because of the accessibility
and differentiation potential of the tissue. Dental pulp has an early developmental origin with …

Gingiva as a source of stem cells with therapeutic potential

BPJ Fournier, H Larjava, L Häkkinen - Stem cells and development, 2013 - liebertpub.com
Postnatal connective tissues contain phenotypically heterogeneous cells populations that
include distinct fibroblast subpopulations, pericytes, myofibroblasts, fibrocytes, and tissue …

Human dental pulp pluripotent-like stem cells promote wound healing and muscle regeneration

E Martínez-Sarrà, S Montori, C Gil-Recio… - Stem cell research & …, 2017 - Springer
Background Dental pulp represents an easily accessible autologous source of adult stem
cells. A subset of these cells, named dental pulp pluripotent-like stem cells (DPPSC), shows …

HDAC inhibitor trichostatin A promotes proliferation and odontoblast differentiation of human dental pulp stem cells

H Jin, JY Park, H Choi, PH Choung - Tissue Engineering Part A, 2013 - liebertpub.com
Trichostatin A (TSA) is a potent histone deacetylase (HDAC) inhibitor with a broad spectrum
of epigenetic activities known to regulate diverse cellular mechanisms, including …

Engineering bone tissue using human dental pulp stem cells and an osteogenic collagen-hydroxyapatite-poly (l-lactide-co-ɛ-caprolactone) scaffold

A Akkouch, Z Zhang… - Journal of biomaterials …, 2014 - journals.sagepub.com
The aim of this study was to design a new natural/synthetic bioactive bone scaffold for
potential use in bone replacement applications. We developed a tri-component osteogenic …

Biodentine Boosts, WhiteProRoot®MTA Increases and Life® Suppresses Odontoblast Activity

A Paula, M Laranjo, CM Marto, AM Abrantes… - Materials, 2019 - mdpi.com
(1) Background: When pulp exposure occurs, reparative dentinogenesis can be induced by
direct pulp capping to maintain the vitality and function of the tissue. The aim of this work …

Osteogenic potential of dental mesenchymal stem cells in preclinical studies: a systematic review using modified ARRIVE and CONSORT guidelines

M Ramamoorthi, M Bakkar, J Jordan… - Stem cells …, 2015 - Wiley Online Library
Background and Objective. Dental stem cell‐based tissue engineered constructs are
emerging as a promising alternative to autologous bone transfer for treating bone defects …

Evaluation of dentinogenesis inducer biomaterials: an in vivo study

AB Paula, M Laranjo, CM Marto, S Paulo… - Journal of Applied Oral …, 2019 - SciELO Brasil
When exposure of the pulp to external environment occurs, reparative dentinogenesis can
be induced by direct pulp capping to maintain pulp tissue vitality and function. These clinical …