Coronary microvascular dysfunction: mechanisms and functional assessment

PG Camici, G d'Amati, O Rimoldi - Nature Reviews Cardiology, 2015 - nature.com
Obstructive disease of the epicardial coronary arteries was recognized as the cause of
angina pectoris> 2 centuries ago, and sudden thrombotic occlusion of an epicardial …

Pathophysiology and diagnosis of coronary microvascular dysfunction in ST-elevation myocardial infarction

LSF Konijnenberg, P Damman… - Cardiovascular …, 2020 - academic.oup.com
Early mechanical reperfusion of the epicardial coronary artery by primary percutaneous
coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation …

Prognostic value of the index of microcirculatory resistance measured after primary percutaneous coronary intervention

WF Fearon, AF Low, AS Yong, R McGeoch, C Berry… - Circulation, 2013 - Am Heart Assoc
Background—Most methods for assessing microvascular function are not readily available
in the cardiac catheterization laboratory. The aim of this study is to determine whether the …

Invasive assessment of the coronary microvasculature: the index of microcirculatory resistance

WF Fearon, Y Kobayashi - Circulation: Cardiovascular …, 2017 - Am Heart Assoc
Traditionally, invasive coronary physiological assessment has focused on the epicardial
coronary artery. More recently, appreciation of the importance of the coronary …

Fractional flow reserve for the assessment of nonculprit coronary artery stenoses in patients with acute myocardial infarction

A Ntalianis, JW Sels, G Davidavicius, N Tanaka… - JACC: Cardiovascular …, 2010 - jacc.org
Objectives: We investigated the reliability of fractional flow reserve (FFR) of nonculprit
coronary stenoses during percutaneous coronary intervention (PCI) in acute myocardial …

Invasive assessment of the coronary microcirculation: superior reproducibility and less hemodynamic dependence of index of microcirculatory resistance compared …

MKC Ng, AC Yeung, WF Fearon - Circulation, 2006 - Am Heart Assoc
Background—A simple, reproducible invasive method for assessing the coronary
microcirculation is lacking. A novel index of microcirculatory resistance (IMR) has been …

Coronary angiography-derived index of microvascular resistance

H Ai, Y Feng, Y Gong, B Zheng, Q Jin… - Frontiers in …, 2020 - frontiersin.org
A coronary angiography-derived index of microvascular resistance (caIMR) is proposed for
physiological assessment of microvasular diseases in coronary circulation. The aim of the …

Catheter-based measurements of absolute coronary blood flow and microvascular resistance: feasibility, safety, and reproducibility in humans

P Xaplanteris, S Fournier, DCJ Keulards… - Circulation …, 2018 - Am Heart Assoc
Background—The principle of continuous thermodilution can be used to calculate absolute
coronary blood flow and microvascular resistance (R). The aim of the study is to explore the …

Predictive value of the index of microcirculatory resistance in patients with ST-segment elevation myocardial infarction

WF Fearon, M Shah, M Ng, T Brinton, A Wilson… - Journal of the American …, 2008 - jacc.org
Objectives: The objective of this study is to evaluate the predictive value of the index of
microcirculatory resistance (IMR) in patients undergoing primary percutaneous coronary …

Diagnosis of coronary microvascular dysfunction in the clinic

P Ong, B Safdar, A Seitz, A Hubert… - Cardiovascular …, 2020 - academic.oup.com
The coronary microcirculation plays a pivotal role in the regulation of coronary blood flow
and cardiac metabolism. It can adapt to acute and chronic pathologic conditions such as …