Lung transplantation has been established worldwide as the last treatment for end-stage
respiratory failure. However, ischemia–reperfusion injury (IRI) inevitably occurs after lung …

Thoracic surgery has evolved drastically in recent years. Although thoracic surgeons mainly
deal with tumorous lesion in the lungs, mediastinum, and pleura, they also perform lung …

Abstract MiR-21-5p is an anti-apoptotic miRNA known to mediate the protective effect of
mesenchymal stromal cell-secreted exosomes (MSC-Exo) against oxidative stress-induced …

Ischemia-reperfusion injury is a common early complication after lung transplantation. It was
reported that long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma …

BACKGROUND Lung ischemia/reperfusion (IR) injury contributes to the development of
severe complications in patients undergoing transplantation. Mesenchymal stem cell (MSC) …

Background Necroptosis plays an important role in cell death during pulmonary ischemia-
reperfusion injury (IRI). We hypothesized that therapy with necrosulfonamide (NSA), a mixed …

The clinical results of lung transplantation (LTx) are still less favorable than other solid organ
transplants in both the early and long term. The fragility of the lungs limits the procurement …

Objective Lung ischemia-reperfusion injury is among the complications seen after lung
transplantation, resulting in morbidity and mortality. Pirfenidone, an antifibrotic agent for the …

The endothelial glycocalyx is a thin layer consisting of proteoglycans, glycoproteins and
glycosaminoglycans that lines the luminal side of vascular endothelial cells. It acts as a …

Lung transplantation (LTx) is the gold standard treatment for end-stage lung disease;
however, waitlist mortality remains high due to a shortage of suitable donor lungs. Organ …