The contribution of copy number variants to psychiatric symptoms and cognitive ability

J Mollon, L Almasy, S Jacquemont, DC Glahn - Molecular psychiatry, 2023 - nature.com
Copy number variants (CNVs) are deletions and duplications of DNA sequence. The most
frequently studied CNVs, which are described in this review, are recurrent CNVs that occur …

Hidden role of gut microbiome dysbiosis in schizophrenia: Antipsychotics or psychobiotics as therapeutics?

N Munawar, K Ahsan, K Muhammad, A Ahmad… - International journal of …, 2021 - mdpi.com
Schizophrenia is a chronic, heterogeneous neurodevelopmental disorder that has complex
symptoms and uncertain etiology. Mounting evidence indicates the involvement of genetics …

[HTML][HTML] Child and adolescent mental health disorders in the GCC: A systematic review and meta-analysis

MF Chan, R Al Balushi, M Al Falahi… - International Journal of …, 2021 - Elsevier
Abstract Background The Gulf Cooperation Council (GCC), with a predominant 'youth
bulge'among its 54 million people, has witnessed an exponential increase in research …

Schizophrenia: a developmental disorder with a risk of non-specific but avoidable decline

RM Murray, E Bora, G Modinos, A Vernon - Schizophrenia Research, 2022 - Elsevier
The onset of schizophrenia is determined by biological and social risk factors operating
predominantly during development. These result in subtle deviations in brain structure and …

Etiopathogenesis of schizophrenia-the state of the art for 2021.

J Rybakowski - Psychiatria polska, 2021 - europepmc.org
In 2021, one-hundred and ten years passed since a Swiss psychiatrist, Eugen Bleuler,
introduced a term‛ schizophrenia', denoting one of the most severe and stigmatizing …

A review of the cognitive impact of neurodevelopmental and neuropsychiatric associated copy number variants

CJ Molloy, C Quigley, Á McNicholas, L Lisanti… - Translational …, 2023 - nature.com
The heritability of intelligence or general cognitive ability is estimated at 41% and 66% in
children and adults respectively. Many rare copy number variants are associated with …

The Risk for Schizophrenia–Bipolar Spectrum: Does the Apple Fall Close to the Tree? A Narrative Review

G Cattarinussi, AA Gugliotta, F Sambataro - International journal of …, 2023 - mdpi.com
Schizophrenia (SCZ) and bipolar disorder (BD) are severe psychiatric disorders that share
clinical features and several risk genes. Important information about their genetic …

Cognitive impairment in psychiatric diseases: Biomarkers of diagnosis, treatment, and prevention

Y Wang, W Meng, Z Liu, Q An, X Hu - Frontiers in Cellular …, 2022 - frontiersin.org
Psychiatric diseases, such as schizophrenia, bipolar disorder, autism spectrum disorder,
and major depressive disorder, place a huge health burden on society. Cognitive …

Transcriptome-wide association study reveals two genes that influence mismatch negativity

A Bhat, H Irizar, JH Thygesen, K Kuchenbaecker… - Cell Reports, 2021 - cell.com
Mismatch negativity (MMN) is a differential electrophysiological response measuring cortical
adaptability to unpredictable stimuli. MMN is consistently attenuated in patients with …

Overlap between genetic variants associated with schizophrenia spectrum disorders and intelligence quotient: a systematic review

N Murillo-García, S Barrio-Martínez… - Journal of Psychiatry and …, 2022 - jpn.ca
Background: To study whether there is genetic overlap underlying the risk for schizophrenia
spectrum disorders (SSDs) and low intelligence quotient (IQ), we reviewed and summarized …