Highlights•More than 60 zebrafish chemical screens have been reported since 2000.•We
summarize the current practices in design of high-throughput zebrafish screens.•We …

The interactions of nanomedicines with biological environments is heavily influenced by
their physicochemical properties. Formulation design and optimization are therefore key …

The rise of Free and Open Source models for software development has catalyzed the
growth of Free and Open Source Hardware (also known as “Libre Hardware”). Libre …

Zebrafish xenotransplantation models are increasingly applied for phenotypic drug
screening to identify small compounds for precision oncology. Larval zebrafish xenografts …

Genetic disorders account for a wide range of renal diseases emerging during childhood
and adolescence. Due to the utilization of modern biochemical and biomedical techniques …

High-efficiency zebrafish (embryo) handling platforms are crucially needed to facilitate the
deciphering of the increasingly expanding vertebrate–organism model values. However, the …

Cancer metastasis is the most important prognostic factor determining patient survival, but
currently there are very few drugs or therapies that specifically inhibit the invasion and …

The EU-EuroMix project adopted the strategy of the European Food Safety Authority (EFSA)
for cumulative risk assessment, which limits the number of chemicals to consider in a mixture …

Background FSGS affects the complex three-dimensional morphology of podocytes,
resulting in loss of filtration barrier function and the development of sclerotic lesions …

The combination of open-source software and hardware provides technically feasible
methods to create low-cost, highly customized scientific research equipment. Open-source 3 …