Per gram of tissue, the kidneys are among our most highly perfused organs. Yet the renal
cortex and, in particular, the renal medulla are susceptible to hypoxia. In turn, hypoxia is a …

Computational models have made a major contribution to the field of physiology. As the
complexity of our understanding of biological systems expands, the need for computational …

The availability of oxygen in renal tissue is determined by the complex interactions among a
host of processes, including renal blood flow, glomerular filtration, arterial-to-venous oxygen …

Countercurrent systems have evolved in a variety of biological systems that allow transfer of
heat, gases, and solutes. For example, in the renal medulla, the countercurrent arrangement …

We assessed the utility of synchrotron‐radiation micro‐computed tomography (micro‐CT) for
quantification of the radial geometry of the renal cortical vasculature. The kidneys of nine …

Oxygen is unlikely to be shunted along the preglomerular vasculature in sufficient quantities
to affect renal oxygenation. There may be substantial shunting at the level of the …

The aim of this study was to evaluate whether possible preglomerular arterial-to-venous
oxygen shunting is affected by the interaction between renal preglomerular carbon dioxide …

Countercurrent systems have evolved in a variety of biological systems that allow transfer of
27 heat, gases and solutes. For example, in the renal medulla, the countercurrent …