Cortisol and major depressive disorder—translating findings from humans to animal models and back

LS Nandam, M Brazel, M Zhou, DJ Jhaveri - Frontiers in psychiatry, 2020 - frontiersin.org
Major depressive disorder (MDD) is a global problem for which current pharmacotherapies
are not completely effective. Hypothalamic–pituitary–adrenal (HPA) axis dysfunction has …

Childhood maltreatment and inflammatory markers: a systematic review

R Coelho, TW Viola, C Walss‐Bass… - Acta Psychiatrica …, 2014 - Wiley Online Library
Objective Childhood maltreatment (CM) has been associated with several diseases in adult
life, including diabetes, obesity and mental disorders. Inflammatory conditions have been …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Comorbidities and continuities as ontogenic processes: Toward a developmental spectrum model of externalizing psychopathology

TP Beauchaine, T McNulty - Development and psychopathology, 2013 - cambridge.org
Research on child and adolescent mental health problems has burgeoned since the
inaugural issue of Development and Psychopathology was published in 1989. In the quarter …

Cortisol and depression: three questions for psychiatry

J Herbert - Psychological medicine, 2013 - cambridge.org
BackgroundCortisol plays a multifaceted role in major depression disorder (MDD). Diurnal
rhythms are disturbed, there is increased resistance to the feedback action of …

Characterizing adverse childhood experiences among children and adolescents with prenatal alcohol exposure and fetal alcohol spectrum disorder

K Flannigan, A Kapasi, J Pei, I Murdoch, G Andrew… - Child Abuse & …, 2021 - Elsevier
Abstract Background Individuals with Fetal Alcohol Spectrum Disorder (FASD) and prenatal
alcohol exposure (PAE) face elevated rates of postnatal environmental adversity across the …

An overview of prevention of multiple risk behaviour in adolescence and young adulthood

CA Jackson, M Henderson, JW Frank… - Journal of public …, 2012 - academic.oup.com
The observed clustering, and shared underlying determinants, of risk behaviours in young
people has led to the proposition that interventions should take a broader approach to risk …

HPA axis responses to psychological challenge linking stress and disease: What do we know on sources of intra-and interindividual variability?

S Zänkert, S Bellingrath, S Wüst, BM Kudielka - Psychoneuroendocrinology, 2019 - Elsevier
Stress is an ubiquitous phenomenon with significant impact on human physiology when it
lasts too long, when it is too intense, or when it hits vulnerable individuals. Examining the …

Stress hormones in psychophysiological research: emotional, behavioral, and cognitive implications.

WR Lovallo, TW Buchanan - 2017 - psycnet.apa.org
This chapter describes regulation of the stress hormones and their measurement and
interpretation in psychophysiological research. A hormone is a signaling molecule, secreted …

Interventions to improve cortisol regulation in children: a systematic review

N Slopen, KA McLaughlin, JP Shonkoff - Pediatrics, 2014 - publications.aap.org
Childhood adversity is associated with physiologic dysregulation across multiple biological
systems; however, relatively little is known about whether these changes are reversible with …