Congenital heart disease (CHD) is often comprised of complex three-dimensional (3D)
anatomy that must be well understood to assess the pathophysiological consequences and …

Bicuspid aortic valve is the most common congenital heart disease and exposes patients to
an increased risk of aortic dilation and dissection. Aortic dilation is a slow, silent process …

Objectives This study sought to assess the predictive value of wall shear stress (WSS) for
colocalized ascending aorta (AAo) growth rate (GR) in patients with bicuspid aortic valve …

Background: Blood flow patterns can alter material properties of ascending thoracic aortic
aneurysms (ATAA) via vascular wall remodeling. This study examines the relationship …

Congenital bicuspid aortic valve (BAV) consists of two fused cusps and represents a major
risk factor for calcific valvular stenosis. Herein, a fully coupled fluid–structure interaction (FSI) …

Background: The primary objective of this review was to explore the contribution of oxidative
stress to the pathogenesis of genetically-triggered thoracic aortic aneurysm (TAA) …

Blood flow in the aorta is helical, but most computational studies ignore the presence of
secondary flow components at the ascending aorta (AAo) inlet. The aim of this study is to …

The aortopathy associated with bicuspid aortic valve (BAV) is an epidemiologically relevant
source of chronic and acute aortic disease (aneurysm and dissection). However, its …

Purpose Current intervention guidelines for bicuspid aortic valve (BAV) associated
ascending aorta (AAo) dilatation are suboptimal predictors of clinical outcome. There is …

Objective: To assess the relationship between regional wall shear stress (WSS) and
oscillatory shear index (OSI) and aortic dilation in patients with bicuspid aortic valve (BAV) …