Thymoquinone and its therapeutic potentials

S Darakhshan, AB Pour, AH Colagar… - Pharmacological …, 2015 - Elsevier
Herbal medicine has attracted great attention in the recent years and is increasingly used as
alternatives to chemical drugs. Several lines of evidence support the positive impact of …

Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin

SN Goyal, CP Prajapati, PR Gore, CR Patil… - Frontiers in …, 2017 - frontiersin.org
Thymoquinone, a monoterpene molecule is chemically known as 2-methyl-5-isopropyl-1, 4-
benzoquinone. It is abundantly present in seeds of Nigella sativa L. that is popularly known …

[HTML][HTML] Thymoquinone: A novel strategy to combat cancer: A review

M Imran, A Rauf, IA Khan, M Shahbaz… - Biomedicine & …, 2018 - Elsevier
The higher consumption of fruit, herbs, spices, and vegetables is well known and practical
strategy to cure human cancers owing to their presence of bioactive compounds. Among …

[HTML][HTML] Cancer: Thymoquinone antioxidant/pro-oxidant effect as potential anticancer remedy

YK Mahmoud, HMA Abdelrazek - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Recently, there is growing interest in the natural bioactive components having anticancer
activity. Thymoquinone (TQ), the principle active constituent of black seed (Nigella sativa) …

[HTML][HTML] Thymoquinone: an emerging natural drug with a wide range of medical applications

M Khader, PM Eckl - Iranian journal of basic medical sciences, 2014 - ncbi.nlm.nih.gov
Nigella sativa has attracted healers in ancient civilizations and researchers in recent times.
Traditionally, it has been used in different forms to treat many diseases including asthma …

Thymoquinone: fifty years of success in the battle against cancer models

R Schneider-Stock, IH Fakhoury, AM Zaki… - Drug discovery today, 2014 - Elsevier
Highlights•This year marks 50 years since thymoquinone was isolated from black
seed.•Thymoquinone has had a long history of battling cancer in vitro and in …

The modulatory potential of herbal antioxidants against oxidative stress and heavy metal pollution: plants against environmental oxidative stress

O Navid, NA Amir, NA Amin, LK Bagheri… - Environmental …, 2021 - search.proquest.com
Free radicals, principally reactive oxygen species (ROS), contribute to oxidative stress in
human beings. Free radicals have different mechanisms of action and affect lipids, proteins …

Mechanisms of thymoquinone hepatorenal protection in methotrexate‐induced toxicity in rats

AAK El-Sheikh, MA Morsy, AM Abdalla… - Mediators of …, 2015 - Wiley Online Library
To investigate mechanisms by which thymoquinone (TQ) can prevent methotrexate‐(MTX‐)
induced hepatorenal toxicity, TQ (10 mg/kg) was administered orally for 10 days. In …

Adverse effects of organophosphorus pesticides on the liver: a brief summary of four decades of research

S Karami-Mohajeri, A Ahmadipour… - Arhiv za higijenu rada i …, 2017 - hrcak.srce.hr
Sažetak Organophosphorus pesticides (OPs) are widely used volatile pesticides that have
harmful effects on the liver in acute and chronic exposures. This review article summarises …

[HTML][HTML] Black seed (Nigella sativa) and its constituent thymoquinone as an antidote or a protective agent against natural or chemical toxicities

A Tavakkoli, A Ahmadi, BM Razavi… - Iranian journal of …, 2017 - ncbi.nlm.nih.gov
Abstract Nigella sativa (N. sativa), which belongs to the botanical family of Ranunculaceae,
is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used …