Proper muscle function constitutes a precondition for good heath and an active lifestyle
during an individual's lifespan and any deviations from normal skeletal muscle development …

In patients with chronic kidney disease (CKD), loss of cellular proteins increases the risks of
morbidity and mortality. Persistence of muscle protein catabolism in CKD results in striking …

Chronic kidney disease (CKD) accelerates muscle protein degradation by stimulating the
ubiquitin proteasome system through activation of the E3 ligases, Atrogin-1/MAFbx and …

MicroRNA in myogenesis and muscle atrophy : Current Opinion in Clinical Nutrition &
Metabolic Care MicroRNA in myogenesis and muscle atrophy : Current Opinion in Clinical …

Duchenne muscular dystrophy (DMD) is caused by mutations in the gene encoding
dystrophin, which results in dysfunctional signaling pathways within muscle. Previously, we …

In patients with Duchenne muscular dystrophy (DMD), the absence of a functional
dystrophin protein results in sarcolemmal instability, abnormal calcium signaling …

Skeletal muscle possesses a strong ability to regenerate following injury, a fact that has
been largely attributed to satellite cells. Satellite cells are skeletal muscle stem cells located …

MicroRNAs (miRNAs) are a class of small RNAs that regulate gene expression and are
implicated in wide-ranging cellular processes and pathological conditions including …

Myostatin, also known as growth and differentiation factor-8, is a pivotal negative regulator of
skeletal muscle mass and reduces muscle protein synthesis by inhibiting the insulin-like …

MicroRNAs (miRNAs) have emerged as important players in the regulation of gene
expression, being involved in most biological processes examined to date. The proposal …