Nucleophosmin (NPM1) is a well‐known nucleocytoplasmic shuttling protein that performs
several cellular functions such as ribosome biogenesis, chromatin remodeling, genomic …

Numerical and/or structural centrosome amplification (CA) is a hallmark of cancers that is
often associated with the aberrant tumor karyotypes and poor clinical outcomes …

The epidermis is a stratified epithelium that functions as the first line of defense against
pathogenic invasion and acts as a barrier preventing water loss. In this study, we aimed to …

Somatic mutations in the nucleophosmin (NPM1) gene occur in approximately 30% of de
novo acute myeloid leukemias (AMLs) and are relatively enriched in normal karyotype …

Background Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant disease with a
poor prognosis. More effective biomarkers and treatment options remain to be discovered …

Acute myeloid leukemia (AML), the most common acute leukemia in adults, increases
exponentially with age. While a number of recent advances have improved treatment, high …

Multiple isoforms of 14-3-3 proteins exist in different organisms. In mammalian cells, 14-3-3
protein has seven isoforms (α/β, ε, η, γ, σ, θ/τ, and δ/ζ), with α and δ representing the …

Abstract The 14-3-3 family proteins are phosphoserine/phosphothreonine binding proteins
constituting a conserved class of proteins which are detected in all eukaryotic cells. In …

Minichromosome maintenance (MCM) proteins facilitate replication by licensing origins and
unwinding the DNA double strand. Interestingly, the number of MCM hexamers greatly …

In our cells, a limited number of RNA binding proteins (RBPs) are responsible for all aspects
of RNA metabolism across the entire transcriptome. To accomplish this, RBPs form …