An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …

Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

The mechanisms underlying immunomodulatory ability of mesenchymal stromal cells
(MSCs) remain unknown. Recently, studies suggested that the immunomodulatory activity of …

The predominant mechanism by which adipose mesenchymal stem cells (AMSCs)
participate to tissue repair is through a paracrine activity and their communication with the …

Extra-cellular vesicles (EVs) are bilayer membrane structures enriched with proteins, nucleic
acids, and other active molecules and have been implicated in many physiological and …

A substantial proportion of patients with acute graft-versus-host disease (aGVHD) respond to
cell therapy with culture-expanded human bone marrow mesenchymal stromal/stem cells …

Mesenchymal stem cells (MSCs) have been reported to possess regulatory functions on
immune cells which make them alternative therapeutics for the treatment of inflammatory …

Undesired immune responses have drastically hampered outcomes after allogeneic organ
transplantation and cell therapy, and also lead to inflammatory diseases and autoimmunity …

Mesenchymal stromal cells (MSCs) are attractive agents for the prophylaxis of acute graft-
versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (allo …