In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of
intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity …

The discovery that submicron-sized extracellular vesicles (EVs) are generated by both
prokaryotic and eukaryotic cells might have a profound effect on experimental and clinical …

Protein targets in autoimmune disease vary in location, originating within cells as in system
lupus erythematosus (SLE), or found on cell surfaces or in extracellular spaces. The term …

This study is to investigate the inhibitory effects and mechanisms of DEK‐targeting aptamer
(DTA‐64) on epithelial mesenchymaltransition (EMT)‐mediated airway remodelling in mice …

In recent years, neutrophil extracellular traps at the forefront of neutrophil biology have
proven to help capture and kill pathogens involved in the inflammatory process. There is …

DEK protein is critical to the formation of neutrophil extracellular traps (NETs) in rheumatoid
arthritis (RA). Blocking DEK using the aptamer DTA via articular injection has been shown to …

Circulating extracellular vesicles (EVs) are membrane-bound nanoparticles secreted by
most cells for intracellular communication and transportation of biomolecules. EVs carry …

Within the field of regenerative medicine, many have sought to use stem cells as a promising
way to heal human tissue; however, in the past few years, exosomes (packaged vesicles …

Novel therapeutics are required for improving the management of chronic inflammatory
diseases. Aptamers are single-stranded RNA or DNA molecules that have recently shown …

Alopecia areata (AA) is a chronic, multifactorial, polygenic, and heterogeneous disorder
affecting growing hair follicles in susceptible individuals, which results in a non-scarring and …