Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health

T Li, Z Wang, J Guo, C de la Fuente-Nunez… - Science of The Total …, 2023 - Elsevier
The spread of bacterial drug resistance has posed a severe threat to public health globally.
Here, we cover bacterial resistance to current antibacterial drugs, including traditional herbal …

Antimicrobial peptides: mechanism of action, activity and clinical potential

QY Zhang, ZB Yan, YM Meng, XY Hong, G Shao… - Military Medical …, 2021 - Springer
The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Current understanding of modes of action of multicomponent bioactive phytochemicals: Potential for nutraceuticals and antimicrobials

M Wink - Annual Review of Food Science and Technology, 2022 - annualreviews.org
Plants produce a diversity of plant secondary metabolites (PSMs), which function as defense
chemicals against herbivores and microorganisms but also as signal compounds. An …

Haemocyte‐mediated immunity in insects: Cells, processes and associated components in the fight against pathogens and parasites

I Eleftherianos, C Heryanto, T Bassal, W Zhang… - …, 2021 - Wiley Online Library
The host defence of insects includes a combination of cellular and humoral responses. The
cellular arm of the insect innate immune system includes mechanisms that are directly …

Membrane-interacting antifungal peptides

C Struyfs, BPA Cammue, K Thevissen - Frontiers in cell and …, 2021 - frontiersin.org
The incidence of invasive fungal infections is increasing worldwide, resulting in more than
1.6 million deaths every year. Due to growing antifungal drug resistance and the limited …

Can medicinal mushrooms have prophylactic or therapeutic effect against COVID‐19 and its pneumonic superinfection and complicating inflammation?

G Hetland, E Johnson… - Scandinavian journal …, 2021 - Wiley Online Library
Medicinal mushrooms have documented effects against different diseases, including
infections and inflammatory disorders. The related Basidiomycota Agaricus blazei Murill …

Emerging therapeutic options in the management of diabetes: recent trends, challenges and future directions

MA Ansari, W Chauhan, S Shoaib… - International Journal of …, 2023 - nature.com
Diabetes is a serious health issue that causes a progressive dysregulation of carbohydrate
metabolism due to insufficient insulin hormone, leading to consistently high blood glucose …

Marine invertebrate peptides: Antimicrobial peptides

R Wu, J Patocka, E Nepovimova, P Oleksak… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial peptides are an important component of many organisms' innate immune
system, with a good inhibitory or killing effect against the invading pathogens. As a type of …

MicroRNA and gut microbiota: Tiny but mighty—Novel insights into their cross-talk in inflammatory bowel disease pathogenesis and therapeutics

M Casado-Bedmar, E Viennois - Journal of Crohn's and Colitis, 2022 - academic.oup.com
Abstract MicroRNAs [miRNAs], small non-coding RNAs, have recently been described as
crucial contributors to intestinal homeostasis. They can interact with the gut microbiota in a …

Immunomodulatory properties of host defence peptides in skin wound healing

M Petkovic, MV Mouritzen, B Mojsoska, H Jenssen - Biomolecules, 2021 - mdpi.com
Cutaneous wound healing is a vital biological process that aids skin regeneration upon
injury. Wound healing failure results from persistent inflammatory conditions observed in …